An exploration on the toxicity mechanisms of phytotoxins and their potential utilities

H Chen, H Singh, N Bhardwaj… - Critical Reviews in …, 2022 - Taylor & Francis
Phytotoxins are poisonous substances synthesized by plants or plant pathogens through
naturally occurring biochemical reactions. Plants use them as defensive agents against …

Plant-derived toxin inhibitors as potential candidates to complement antivenom treatment in snakebite envenomations

AAX Adrião, AO Dos Santos, EJSP de Lima… - Frontiers in …, 2022 - frontiersin.org
Snakebite envenomations (SBEs) are a neglected medical condition of global importance
that mainly affect the tropical and subtropical regions. Clinical manifestations include pain …

Perspective on the therapeutics of anti-snake venom

I Gómez-Betancur, V Gogineni, A Salazar-Ospina… - Molecules, 2019 - mdpi.com
Snakebite envenomation is a life-threatening disease that was recently re-included as a
neglected tropical disease (NTD), affecting millions of people in tropical and subtropical …

Unraveling snake venom phospholipase A2: an overview of its structure, pharmacology, and inhibitors

GH Sampat, K Hiremath, J Dodakallanavar… - Pharmacological …, 2023 - Springer
Snake bite is a neglected disease that affects millions of people worldwide. WHO reported
approximately 5 million people are bitten by various species of snakes each year, resulting …

The potential of Brazilian native plant species used in the therapy for snakebites: A literature review

EL Konrath, I Strauch, DD Boeff, MD Arbo - Toxicon, 2022 - Elsevier
Snakebite envenoming is a potentially fatal disease categorized as a neglected public
health issue for not receiving the appropriate attention from national and international health …

The anti-snake activity of Nectandra angustifolia flavonoids on phospholipase A2: In vitro and in silico evaluation

AM Torres, GA Ojeda, E Angelina, S Bustillo… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance Lauraceae family includes Nectandra angustifolia a
species widely used in the folk medicine of South America against various maladies. It is …

[PDF][PDF] Gold‐Catalyzed Oxidative Cycloadditions to Activate a Quinoline Framework

DB Huple, S Ghorpade, RS Liu - Chemistry–A European Journal, 2013 - researchgate.net
One advent in gold catalysis is to generate α-oxo gold carbenes [1] by an intermolecular
oxidation of terminal alkynes by using pyridine-based oxide derivatives [2, 3] with 8 …

Implications of phytochemicals in snakebite management: present status and future prospective

NAN Urs, M Yariswamy, V Joshi, A Nataraju… - Toxin …, 2014 - Taylor & Francis
In spite of vast advances in healthcare services, treatment of snakebite still remains a
challenge to medical fraternity, because of unresolved complications of severe local tissue …

Plant steroids: occurrence, biological significance, and their analysis

GMKB Gunaherath… - Encyclopedia of Analytical …, 2006 - Wiley Online Library
Plant steroids constitute a diverse group of natural products. Biosynthetically, they are
derived from S‐squalene‐2, 3‐epoxide via acetate‐mevalonate pathway. Among the plant …

Alkaloids from Siparuna (Siparunaceae) are predicted as the inhibitors of proteolysis and plasma coagulation caused by snake venom and potentially counteract …

DA Fernandes, BA Gomes, SC Mendonça… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Snakebite envenomation (SBE) is the world's most lethal
neglected tropical disease. Bothrops jararaca is the species that causes the greatest number …