The clinical symptoms of Parkinson's disease

S Sveinbjornsdottir - Journal of neurochemistry, 2016 - Wiley Online Library
In this review, the clinical features of Parkinson's disease, both motor and non‐motor, are
described in the context of the progression of the disease. Also briefly discussed are the …

The epigenetics of aging and neurodegeneration

R Lardenoije, A Iatrou, G Kenis, K Kompotis… - Progress in …, 2015 - Elsevier
Epigenetics is a quickly growing field encompassing mechanisms regulating gene
expression that do not involve changes in the genotype. Epigenetics is of increasing …

New clinical subtypes of Parkinson disease and their longitudinal progression: a prospective cohort comparison with other phenotypes

SM Fereshtehnejad, SR Romenets, JBM Anang… - JAMA …, 2015 - jamanetwork.com
Importance There is increasing evidence that Parkinson disease (PD) is heterogeneous in
its clinical presentation and prognosis. Defining subtypes of PD is needed to better …

MDS Task Force on mild cognitive impairment in Parkinson's disease: critical review of PD‐MCI

I Litvan, D Aarsland, CH Adler, JG Goldman… - Movement …, 2011 - Wiley Online Library
There is controversy regarding the definition and characteristics of mild cognitive impairment
in Parkinson's disease. The Movement Disorder Society commissioned a Task Force to …

The MoCA: well-suited screen for cognitive impairment in Parkinson disease

JC Dalrymple-Alford, MR MacAskill, CT Nakas… - Neurology, 2010 - AAN Enterprises
Objective: To establish the diagnostic accuracy of the Montreal Cognitive Assessment
(MoCA) when screening externally validated cognition in Parkinson disease (PD), by …

Validity of the MoCA and MMSE in the detection of MCI and dementia in Parkinson disease

S Hoops, S Nazem, AD Siderowf, JE Duda, SX Xie… - Neurology, 2009 - AAN Enterprises
Background: Due to the high prevalence of mild cognitive impairment (MCI) and dementia in
Parkinson disease (PD), routine cognitive screening is important for the optimal …

Clinical prevalence of Lewy body dementia

JPM Kane, A Surendranathan, A Bentley… - Alzheimer's research & …, 2018 - Springer
Background The prevalence of dementia with Lewy bodies (DLB) and dementia in
Parkinson's disease (PDD) in routine clinical practice is unclear. Prevalence rates observed …

Gender differences in Parkinson's disease: clinical characteristics and cognition

IN Miller, A Cronin‐Golomb - Movement disorders, 2010 - Wiley Online Library
More men than women are diagnosed with Parkinson's disease (PD), and a number of
gender differences have been documented in this disorder. Examples of clinical …

Effects of physical exercise programs on cognitive function in Parkinson's disease patients: a systematic review of randomized controlled trials of the last 10 years

FC Da Silva, RR Iop, LC de Oliveira, AM Boll… - PloS one, 2018 - journals.plos.org
Background Given the relative importance of cognitive impairment, there was considerable
interest in identifying the cognitive profile of PD patients, in order to ensure specific and …

High risk of cognitive and functional decline after postoperative delirium: a three-year prospective study

H Bickel, R Gradinger, E Kochs, H Förstl - Dementia and geriatric …, 2008 - karger.com
Abstract Background/Aims: The aim of the study was to investigate the association of
postoperative delirium with the outcomes of cognitive impairment, functional disability and …