Serotonin is a phylogenetically ancient biogenic amine that has played an integral role in
maintaining energy homeostasis for billions of years. In mammals, serotonin produced …

Atypical antipsychotics (AAPs) are commonly prescribed medications to treat schizophrenia,
bipolar disorders and other psychotic disorders. However, they might cause metabolic …

The exact physiological role for the monoamine serotonin (5‐HT) in modulation of insulin
secretion is yet to be fully understood. Although the presence of this monoamine in islets of …

Pregnancy imposes a substantial metabolic burden on women through weight gain and
insulin resistance. Lactation reduces the risk of maternal postpartum diabetes, but the …

Aims/hypothesis Second-generation antipsychotic (SGA) drugs have been associated with
the development of type 2 diabetes and the metabolic syndrome in patients with …

Abstract Objective Ependymin-Related Protein 1 (EPDR1) was recently identified as a
secreted human batokine regulating mitochondrial respiration linked to thermogenesis in …

Gestational diabetes mellitus (GDM) is currently the most common complication of
pregnancy and is defined as a glucose intolerance disorder with recognition during …

Methylation in CpG sites of the PPARGC1A gene (encoding PGC1-α) has been associated
with adiposity, insulin secretion/sensitivity indexes and type 2 diabetes. We assessed the …

Activation of hepatic stellate cells (HSC) plays a crucial role in the liver disease progression
from liver fibrosis/cirrhosis to cancer. Here, we found a rapid change of microenvironment …

Gestational diabetes (GDM) is characterized by a glucose tolerance disorder. This may first
appear during pregnancy or pre-exist before conception as a form of prediabetes, but there …