Interfering with interferons: A critical mechanism for critical COVID-19 pneumonia
HC Su, H Jing, Y Zhang… - Annual Review of …, 2023 - annualreviews.org
Infection with SARS-CoV-2 results in clinical outcomes ranging from silent or benign
infection in most individuals to critical pneumonia and death in a few. Genetic studies in …
infection in most individuals to critical pneumonia and death in a few. Genetic studies in …
Clinical implications of host genetic variation and susceptibility to severe or critical COVID-19
CI van der Made, MG Netea, FL van der Veerdonk… - Genome medicine, 2022 - Springer
Since the start of the coronavirus disease 2019 (COVID-19) pandemic, important insights
have been gained into virus biology and the host factors that modulate the human immune …
have been gained into virus biology and the host factors that modulate the human immune …
Early treatment with pegylated interferon lambda for Covid-19
G Reis, EAS Moreira Silva… - … England Journal of …, 2023 - Mass Medical Soc
Background The efficacy of a single dose of pegylated interferon lambda in preventing
clinical events among outpatients with acute symptomatic coronavirus disease 2019 (Covid …
clinical events among outpatients with acute symptomatic coronavirus disease 2019 (Covid …
The Penn Medicine BioBank: towards a genomics-enabled learning healthcare system to accelerate precision medicine in a diverse population
The Penn Medicine BioBank (PMBB) is an electronic health record (EHR)-linked biobank at
the University of Pennsylvania (Penn Medicine). A large variety of health-related information …
the University of Pennsylvania (Penn Medicine). A large variety of health-related information …
COVID-19 annual update: a narrative review
M Biancolella, VL Colona, L Luzzatto, JL Watt… - Human genomics, 2023 - Springer
Three and a half years after the pandemic outbreak, now that WHO has formally declared
that the emergency is over, COVID-19 is still a significant global issue. Here, we focus on …
that the emergency is over, COVID-19 is still a significant global issue. Here, we focus on …
How to build a fire: the genetics of autoinflammatory diseases
J Zhang, PY Lee, I Aksentijevich… - Annual Review of …, 2023 - annualreviews.org
Systemic autoinflammatory diseases (SAIDs) are a heterogeneous group of disorders
caused by excess activation of the innate immune system in an antigen-independent …
caused by excess activation of the innate immune system in an antigen-independent …
Interferon at the crossroads of SARS-CoV-2 infection and COVID-19 disease
CE Samuel - Journal of Biological Chemistry, 2023 - ASBMB
A novel coronavirus now known as SARS-CoV-2 emerged in late 2019, possibly following a
zoonotic crossover from a coronavirus present in bats. This virus was identified as the …
zoonotic crossover from a coronavirus present in bats. This virus was identified as the …
Genetic Predictors of Comorbid Course of COVID-19 and MAFLD: A Comprehensive Analysis
Metabolic-associated fatty liver disease (MAFLD) and its potential impact on the severity of
COVID-19 have gained significant attention during the pandemic. This review aimed to …
COVID-19 have gained significant attention during the pandemic. This review aimed to …
Detection of isoforms and genomic alterations by high-throughput full-length single-cell RNA sequencing in ovarian cancer
A Dondi, U Lischetti, F Jacob, F Singer… - Nature …, 2023 - nature.com
Understanding the complex background of cancer requires genotype-phenotype information
in single-cell resolution. Here, we perform long-read single-cell RNA sequencing (scRNA …
in single-cell resolution. Here, we perform long-read single-cell RNA sequencing (scRNA …
Three-year outcomes of post-acute sequelae of COVID-19
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection causes post-
acute sequelae of coronavirus disease 2019 (COVID-19)(PASC) in many organ systems …
acute sequelae of coronavirus disease 2019 (COVID-19)(PASC) in many organ systems …