Gilles de la Tourette syndrome

MM Robertson, V Eapen, HS Singer… - Nature reviews Disease …, 2017 - nature.com
Gilles de la Tourette syndrome (GTS) is a childhood-onset neurodevelopmental disorder
that is characterized by several motor and phonic tics. Tics usually develop before 10 years …

[HTML][HTML] Overlapping sleep disturbances in persistent tic disorders and attention-deficit hyperactivity disorder: A systematic review and meta-analysis of …

L Keenan, C Sherlock, J Bramham… - … & Biobehavioral Reviews, 2021 - Elsevier
Abstract Introduction Persistent tic disorders (PTDs) and attention-deficit hyperactivity
disorder (ADHD) are common neurodevelopmental conditions which tend to co-occur. Both …

Synaptic processes and immune-related pathways implicated in Tourette syndrome

F Tsetsos, D Yu, JH Sul, AY Huang, C Illmann… - Translational …, 2021 - nature.com
Tourette syndrome (TS) is a neuropsychiatric disorder of complex genetic architecture
involving multiple interacting genes. Here, we sought to elucidate the pathways that underlie …

Evidence for the placenta-brain axis: multi-omic kernel aggregation predicts intellectual and social impairment in children born extremely preterm

HP Santos Jr, A Bhattacharya, RM Joseph, L Smeester… - Molecular Autism, 2020 - Springer
Background Children born extremely preterm are at heightened risk for intellectual and
social impairment, including Autism Spectrum Disorder (ASD). There is increasing evidence …

Parental age and differential estimates of risk for neuropsychiatric disorders: Findings from the Danish birth cohort

M Janecka, SN Hansen, A Modabbernia… - Journal of the American …, 2019 - Elsevier
Objective Parental age at birth has been shown to affect the rates of a range of
neurodevelopmental disorders, but the understanding of the mechanisms through which it …

Polygenic risk scores derived from a Tourette syndrome genome-wide association study predict presence of tics in the avon longitudinal study of parents and children …

M Abdulkadir, CA Mathews, JM Scharf, D Yu… - Biological …, 2019 - Elsevier
Background Tourette syndrome (TS) has a well-established genetic background, but its
genetic architecture remains largely unknown. The authors investigated the role of polygenic …

Healthy cortical development through adolescence and early adulthood

NJ Forde, L Ronan, MP Zwiers, LJS Schweren… - Brain Structure and …, 2017 - Springer
Adolescence is a period of significant brain changes; however, the effects of age and sex on
cortical development are yet to be fully characterized. Here, we utilized innovative intrinsic …

Transcriptome-wide association study reveals increased neuronal FLT3 expression is associated with Tourette's syndrome

C Liao, V Vuokila, H Catoire, F Akçimen… - Communications …, 2022 - nature.com
Tourette's Syndrome (TS) is a neurodevelopmental disorder that is characterized by motor
and phonic tics. A recent TS genome-wide association study (GWAS) identified a genome …

The dual role of the TSC complex in cancer

J Hartung, C Müller, CF Calkhoven - Trends in Molecular Medicine, 2024 - cell.com
The tuberous sclerosis complex (TSC1/TSC2/TBC1D7) primarily functions to inhibit the
mechanistic target of rapamycin complex 1 (mTORC1), a crucial regulator of cell growth …

[HTML][HTML] Review of the evidence for the management of co-morbid Tic disorders in children and adolescents with attention deficit hyperactivity disorder

MO Ogundele, HF Ayyash - World journal of clinical pediatrics, 2018 - ncbi.nlm.nih.gov
Attention deficit hyperactivity disorder (ADHD) is the most common neurodevelopmental
disorder in children and adolescents, with prevalence ranging between 5% and 12% in the …