The Pharmacological Activities of Crocus sativus L.: A Review Based on the Mechanisms and Therapeutic Opportunities of its Phytoconstituents

M Butnariu, C Quispe, J Herrera-Bravo… - Oxidative medicine …, 2022 - Wiley Online Library
Crocus species are mainly distributed in North Africa, Southern and Central Europe, and
Western Asia, used in gardens and parks as ornamental plants, while Crocus sativus …

Anti-depressant properties of crocin molecules in saffron

SA Siddiqui, A Ali Redha, ER Snoeck, S Singh… - Molecules, 2022 - mdpi.com
Saffron is a valued herb, obtained from the stigmas of the C. sativus Linn (Iridaceae), with
therapeutic effects. It has been described in pharmacopoeias to be variously acting …

Herbal medicine for depression and anxiety: A systematic review with assessment of potential psycho‐oncologic relevance

KS Yeung, M Hernandez, JJ Mao… - Phytotherapy …, 2018 - Wiley Online Library
Anxiety and depression are prevalent among cancer patients, with significant negative
impact. Many patients prefer herbs for symptom relief to conventional medications which …

Therapeutic potential of natural products in treating neurodegenerative disorders and their future prospects and challenges

MH Rahman, J Bajgai, A Fadriquela, S Sharma… - Molecules, 2021 - mdpi.com
Natural products derived from plants, as well as their bioactive compounds, have been
extensively studied in recent years for their therapeutic potential in a variety of …

Bioactivity assessment and toxicity of crocin: a comprehensive review

SH Alavizadeh, H Hosseinzadeh - Food and chemical toxicology, 2014 - Elsevier
Since ancient times, saffron, the dried stigma of the plant Crocus sativus L. has been
extensively used as a spice and food colorant; in folk medicine it has been reputed to be …

Reactive oxygen species in the regulation of synaptic plasticity and memory

CA Massaad, E Klann - Antioxidants & redox signaling, 2011 - liebertpub.com
The brain is a metabolically active organ exhibiting high oxygen consumption and robust
production of reactive oxygen species (ROS). The large amounts of ROS are kept in check …

Herbal medicine for depression, anxiety and insomnia: a review of psychopharmacology and clinical evidence

J Sarris, A Panossian, I Schweitzer, C Stough… - European …, 2011 - Elsevier
Research in the area of herbal psychopharmacology has increased markedly over the past
decades. To date however, a comprehensive review of herbal antidepressant, anxiolytic and …

Phytochemistry, pharmacology, and potential clinical applications of saffron: A review

B Xing, S Li, J Yang, D Lin, Y Feng, J Lu… - Journal of …, 2021 - Elsevier
Ethnopharmacological relevance Saffron, the dried red stigma of the perennial herb Crocus
sativus L.(Iridaceae), is one of the most important and expensive spices in the world. It is …

[HTML][HTML] The effects of Crocus sativus (saffron) and its constituents on nervous system: A review

MR Khazdair, MH Boskabady, M Hosseini… - Avicenna journal of …, 2015 - ncbi.nlm.nih.gov
Saffron or Crocus sativus L.(C. sativus) has been widely used as a medicinal plant to
promote human health, especially in Asia. The main components of saffron are crocin …

Saffron: An old medicinal plant and a potential novel functional food

M José Bagur, GL Alonso Salinas… - Molecules, 2017 - mdpi.com
The spice saffron is made from the dried stigmas of the plant Crocus sativus L. The main use
of saffron is in cooking, due to its ability to impart colour, flavour and aroma to foods and …