Exploring the human microbiome: the potential future role of next-generation sequencing in disease diagnosis and treatment
The interaction between the human microbiome and immune system has an effect on
several human metabolic functions and impacts our well-being. Additionally, the interaction …
several human metabolic functions and impacts our well-being. Additionally, the interaction …
The road to metagenomics: from microbiology to DNA sequencing technologies and bioinformatics
A Escobar-Zepeda, A Vera-Ponce de León… - Frontiers in …, 2015 - frontiersin.org
The study of microorganisms that pervade each and every part of this planet has
encountered many challenges through time such as the discovery of unknown organisms …
encountered many challenges through time such as the discovery of unknown organisms …
MetaBAT, an efficient tool for accurately reconstructing single genomes from complex microbial communities
Grouping large genomic fragments assembled from shotgun metagenomic sequences to
deconvolute complex microbial communities, or metagenome binning, enables the study of …
deconvolute complex microbial communities, or metagenome binning, enables the study of …
A metagenome-wide association study of gut microbiota in type 2 diabetes
Assessment and characterization of gut microbiota has become a major research area in
human disease, including type 2 diabetes, the most prevalent endocrine disease worldwide …
human disease, including type 2 diabetes, the most prevalent endocrine disease worldwide …
One fungus, which genes? Development and assessment of universal primers for potential secondary fungal DNA barcodes
The aim of this study was to assess potential candidate gene regions and corresponding
universal primer pairs as secondary DNA barcodes for the fungal kingdom, additional to ITS …
universal primer pairs as secondary DNA barcodes for the fungal kingdom, additional to ITS …
Substrate-controlled succession of marine bacterioplankton populations induced by a phytoplankton bloom
Phytoplankton blooms characterize temperate ocean margin zones in spring. We
investigated the bacterioplankton response to a diatom bloom in the North Sea and …
investigated the bacterioplankton response to a diatom bloom in the North Sea and …
Metagenomics-a guide from sampling to data analysis
Metagenomics applies a suite of genomic technologies and bioinformatics tools to directly
access the genetic content of entire communities of organisms. The field of metagenomics …
access the genetic content of entire communities of organisms. The field of metagenomics …
MyTaxa: an advanced taxonomic classifier for genomic and metagenomic sequences
C Luo, LM Rodriguez-r… - Nucleic acids …, 2014 - academic.oup.com
Determining the taxonomic affiliation of sequences assembled from metagenomes remains
a major bottleneck that affects research across the fields of environmental, clinical and …
a major bottleneck that affects research across the fields of environmental, clinical and …
pplacer: linear time maximum-likelihood and Bayesian phylogenetic placement of sequences onto a fixed reference tree
Background Likelihood-based phylogenetic inference is generally considered to be the most
reliable classification method for unknown sequences. However, traditional likelihood-based …
reliable classification method for unknown sequences. However, traditional likelihood-based …
Statistical methods for detecting differentially abundant features in clinical metagenomic samples
Numerous studies are currently underway to characterize the microbial communities
inhabiting our world. These studies aim to dramatically expand our understanding of the …
inhabiting our world. These studies aim to dramatically expand our understanding of the …