The chemistry and biological activities of peptides from amphibian skin secretions

X Xu, R Lai - Chemical reviews, 2015 - ACS Publications
Amphibian skin is directly exposed to different environments. Amphibians interact with
environmental factors including microorganisms, parasites, predators, and physical factors …

Peptides: Production, bioactivity, functionality, and applications

M Hajfathalian, S Ghelichi… - Critical reviews in …, 2018 - Taylor & Francis
Production of peptides with various effects from proteins of different sources continues to
receive academic attention. Researchers of different disciplines are putting increasing efforts …

Bioinformatic analysis of 1000 amphibian antimicrobial peptides uncovers multiple length-dependent correlations for peptide design and prediction

G Wang - Antibiotics, 2020 - mdpi.com
Amphibians are widely distributed on different continents, except for the polar regions. They
are important sources for the isolation, purification and characterization of natural …

Antimicrobial peptides as a promising treatment option against Acinetobacter baumannii infections

A Neshani, H Sedighian, SA Mirhosseini… - Microbial …, 2020 - Elsevier
Background With the increasing rate of antibiotic resistance in Acinetobacter, the World
Health Organization introduced the carbapenem-resistant isolates in the priority pathogens …

Host-defense peptides with therapeutic potential from skin secretions of frogs from the family pipidae

JM Conlon, M Mechkarska - Pharmaceuticals, 2014 - mdpi.com
Skin secretions from frogs belonging to the genera Xenopus, Silurana, Hymenochirus, and
Pseudhymenochirus in the family Pipidae are a rich source of host-defense peptides with …

Peptidomic analysis in the discovery of therapeutically valuable peptides in amphibian skin secretions

JM Conlon, M Mechkarska… - Expert Review of …, 2019 - Taylor & Francis
Introduction: The emergence of multidrug-resistant microorganisms has necessitated a
search for new antimicrobial agents. Skin secretions of many frog species contain peptides …

Peptide Dendrimer-Based Antibacterial Agents: Synthesis and Applications

S Paul, S Verma, YC Chen - ACS Infectious Diseases, 2024 - ACS Publications
Pathogenic bacteria cause the deaths of millions of people every year. With the
development of antibiotics, hundreds and thousands of people's lives have been saved …

Peptides from frog skin with potential for development into agents for Type 2 diabetes therapy

JM Conlon, M Mechkarska, YH Abdel-Wahab, PR Flatt - Peptides, 2018 - Elsevier
Several frog skin peptides, first identified as result of their antimicrobial or
immunomodulatory activities, have subsequently been shown to stimulate insulin release …

The potential of frog skin-derived peptides for development into therapeutically-valuable immunomodulatory agents

JM Pantic, IP Jovanovic, GD Radosavljevic… - Molecules, 2017 - mdpi.com
The aim of this article is to review the immunoregulatory actions of frog skin-derived peptides
in order to assess their potential as candidates for immunomodulatory or anti-inflammatory …

Anti-cancer, immunoregulatory, and antimicrobial activities of the frog skin host-defense peptides pseudhymenochirin-1Pb and pseudhymenochirin-2Pa

M Mechkarska, S Attoub, S Sulaiman, J Pantic… - Regulatory …, 2014 - Elsevier
Abstract Pseudhymenochirin-1Pb (Ps-1Pb) and pseudhymenochirin-2Pa (Ps-2Pa) are host-
defense peptides, first isolated from skin secretions of the frog Pseudhymenochirus merlini …