Postbiotics as the new frontier in food and pharmaceutical research

S Sabahi, A Homayouni Rad… - Critical reviews in …, 2023 - Taylor & Francis
Food is the essential need of human life and has nutrients that support growth and health.
Gastrointestinal tract microbiota involves valuable microorganisms that develop therapeutic …

Functional oligosaccharide fermentation in the gut: Improving intestinal health and its determinant factors-A review

N Zhang, M Jin, K Wang, Z Zhang, NP Shah… - Carbohydrate Polymers, 2022 - Elsevier
The human intestine is characterized by an abundance of nutrients and a complex
microbiota that make crucial contributions to overall health. These nutrients facilitate the …

Functional effects of human milk oligosaccharides (HMOs)

M Dinleyici, J Barbieur, EC Dinleyici, Y Vandenplas - Gut Microbes, 2023 - Taylor & Francis
Human milk oligosaccharides (HMOs) are the third most important solid component in
human milk and act in tandem with other bioactive components. Individual HMO levels and …

[HTML][HTML] Clinical evaluation of 16-week supplementation with 5HMO-mix in healthy-term human infants to determine tolerability, safety, and effect on growth

K Parschat, C Melsaether, KR Jäpelt, S Jennewein - Nutrients, 2021 - mdpi.com
Human milk oligosaccharides (HMOs) are complex sugars that occur naturally in human
breast milk and provide many beneficial functions. Most formula products lack HMOs or …

[HTML][HTML] Clinical studies on the supplementation of manufactured human milk Oligosaccharides: A systematic review

YB Schoenknecht, MV Moreno Tovar, SR Jensen… - Nutrients, 2023 - mdpi.com
Human milk oligosaccharides (HMOs) are a major component of human milk. They are
associated with multiple health benefits and are manufactured on a large scale for their …

[HTML][HTML] Current knowledge about the impact of maternal and infant nutrition on the development of the microbiota–gut–brain axis

T Cerdó, A Nieto-Ruíz, JA García-Santos… - Annual Review of …, 2023 - annualreviews.org
The prenatal and early postnatal periods are stages during which dynamic changes and the
development of the brain and gut microbiota occur, and nutrition is one of the most important …

Advances and challenges for obtaining human milk oligosaccharides: Extraction from natural sources and synthesis by intentional design

J Gan, C Cao, B Stahl, X Zhao, J Yan - Trends in Food Science & …, 2023 - Elsevier
Abstract Background Human milk oligosaccharides (HMOs) are a group of structurally
diverse unconjugated carbohydrates that are bioactive and functional beyond their important …

Do Oligosaccharide-Supplemented Infant Formulas Improve Infant Gastrointestinal Health? A Systematic Review of Randomized Clinical Trials

A Leong, C Mori, C Pillidge, H Gill - Food Reviews International, 2024 - Taylor & Francis
Supplementing infant formulas (IFs) with oligosaccharides has gathered much attention over
the years because of their purported disease-protecting and health-promoting properties …

[HTML][HTML] What are normal defecation patterns in healthy children up to four years of age? A systematic review and meta-analysis

DF Baaleman, CAM Wegh, TJM de Leeuw… - The Journal of …, 2023 - Elsevier
Objective To summarize available data on defecation frequency and stool consistency of
healthy children up to age 4 in order to estimate normal references values. Study design …

[HTML][HTML] Bioactive compounds in childhood obesity and associated metabolic complications: Current evidence, controversies and perspectives

G Fiore, MC Pascuzzi, E Di Profio, A Corsello… - Pharmacological …, 2023 - Elsevier
Obesity represents the most frequent chronic disease among children worldwide, with a
significant global burden on society. Metabolically unhealthy obesity (MUO) can affect …