Much effort has been put into the optimization of the functional activity of proteins. For
biosensors this protein functional optimization will increase the biosensor's sensitivity and/or …

Protein synthesis and its relation to the genetic code was for a long time a central issue in
biology. Rapid experimental progress throughout the past decade, crowned with the recently …

More than two decades ago a general method to genetically encode noncanonical or
unnatural amino acids (NAAs) with diverse physical, chemical, or biological properties in …

Industrial biotechnology involves the use of enzymes and microorganisms to produce value‐
added chemicals from renewable sources. Because of its association with reduced energy …

MicroScale Thermophoresis (MST) is a frequently used method for the quantitative
characterization of intermolecular interactions with several advantages over other …

Fourier transform infrared (FTIR) spectroscopy has become one of the major techniques of
structural characterization of proteins, peptides, and protein–membrane interactions. While …

The search for chemical probes which allow a controlled fluorescence activation in living
cells represent a major challenge in chemical biology. To be useful, such probes have to be …

Fourier transform infrared (FTIR) spectroscopy is widely used in structural characterization of
proteins or peptides. While the method does not have the capability of providing the precise …

Nonnatural amino acids have been introduced into proteins using expanded protein
biosynthesis systems. However, some nonnatural amino acids, especially those containing …

The use of fluorine has become well established in the analysis of protein structure and
function, eg in tools such as 19F NMR spectroscopy. The application of the unique electronic …