The human gut virome: composition, colonization, interactions, and impacts on human health

E Pargin, MJ Roach, A Skye, B Papudeshi… - Frontiers in …, 2023 - frontiersin.org
The gut virome is an incredibly complex part of the gut ecosystem. Gut viruses play a role in
many disease states, but it is unknown to what extent the gut virome impacts everyday …

The next generation fecal microbiota transplantation: to transplant bacteria or virome

Y Yu, W Wang, F Zhang - Advanced Science, 2023 - Wiley Online Library
Fecal microbiota transplantation (FMT) has emerged as a promising therapeutic approach
for dysbiosis‐related diseases. However, the clinical practice of crude fecal transplants …

The gut virome is associated with stress-induced changes in behaviour and immune responses in mice

NL Ritz, LA Draper, TFS Bastiaanssen… - Nature …, 2024 - nature.com
The microbiota–gut–brain axis has been shown to play an important role in the stress
response, but previous work has focused primarily on the role of the bacteriome. The gut …

Overcoming donor variability and risks associated with fecal microbiota transplants through bacteriophage-mediated treatments

TS Rasmussen, X Mao, S Forster, SB Larsen… - Microbiome, 2024 - Springer
Background Fecal microbiota transplantation (FMT) and fecal virome transplantation (FVT,
sterile filtrated donor feces) have been effective in treating recurrent Clostridioides difficile …

[HTML][HTML] The role of viruses in the pathogenesis of immune-mediated gastro-intestinal diseases

F Bernardi, F Ungaro, F D'Amico, A Zilli… - International Journal of …, 2024 - mdpi.com
Immune-mediated gastrointestinal (GI) diseases, including achalasia, celiac disease, and
inflammatory bowel diseases, pose significant challenges in diagnosis and management …

[HTML][HTML] Fecal virome transplantation: A promising strategy for the treatment of metabolic diseases

C Zeng, SR Wan, M Guo, XZ Tan, Y Zeng, Q Wu… - Biomedicine & …, 2024 - Elsevier
Metabolic diseases are a group of disorders caused by metabolic abnormalities, including
obesity, diabetes, non-alcoholic fatty liver disease, and more. Increasing research indicates …

[HTML][HTML] Fecal Microbiota Transplantation, a tool to transfer healthy longevity

MG Novelle, B Naranjo, JL López-Cánovas… - Ageing Research …, 2024 - Elsevier
The complex gut microbiome influences host aging and plays an important role in the
manifestation of age-related diseases. Restoring a healthy gut microbiome via Fecal …

Gut virome in inflammatory bowel disease and beyond

HM Tun, Y Peng, L Massimino, ZY Sin, TL Parigi… - Gut, 2024 - gut.bmj.com
Objective The gut virome is a dense community of viruses inhabiting the gastrointestinal tract
and an integral part of the microbiota. The virome coexists with the other components of the …

Transfer of modified gut viromes improves symptoms associated with metabolic syndrome in obese male mice

X Mao, SB Larsen, LSF Zachariassen, A Brunse… - Nature …, 2024 - nature.com
Metabolic syndrome encompasses amongst other conditions like obesity and type-2
diabetes and is associated with gut microbiome (GM) dysbiosis. Fecal microbiota …

Opportunities and challenges in phage therapy for cardiometabolic diseases

K Wortelboer, H Herrema - Trends in Endocrinology & Metabolism, 2024 - cell.com
The worldwide prevalence of cardiometabolic diseases (CMD) is increasing, and emerging
evidence implicates the gut microbiota in this multifactorial disease development …