Foreign‐body response caused by implanted biomaterials seriously impedes the function of
implants and is a major obstacle to the development of implantable biomaterials and …

All biomaterials, when implanted in vivo, elicit cellular and tissue responses. These
responses include the inflammatory and wound healing responses, foreign body reactions …

Surgical implants are essential elements of repair procedures to correct worn out joints,
damaged spinal components, heart and vascular disease, and chronic pain. However, many …

Over the last decade, pedicle fixation systems have evolved and modifications in spinal
fusion techniques have been developed to increase fusion rates and improve clinical …

Metal hypersensitivity (MHS) is a rare complication of total joint arthroplasty that has been
linked to prosthetic device failure when other potential causes have been ruled out. The …

The American Contact Dermatitis Society recognizes the interest in the evaluation and
management of metal hypersensitivity reactions. Given the paucity of robust evidence with …

Aims Metal allergy in knee arthroplasty patients is a controversial topic. We aimed to conduct
a scoping review to clarify the management of metal allergy in primary and revision total …

Hypersensitivity reactions to implants in orthopaedic and trauma surgery are a rare but
devastating complication. They are considered as a delayed-type of hypersensitivity reaction …

Metals and metal alloys are the most used materials in orthopedic implants. The focus is on
total hip arthroplasty (THA) that, though well tolerated, may be associated with local and …

Total joint arthroplasties are increasingly common orthopedic procedures performed
throughout the United States. Implant failure after these procedures occurs due to a number …