Aptamer-functionalized metal-organic frameworks (MOFs) for biosensing

M Lv, W Zhou, H Tavakoli, C Bautista, J Xia… - Biosensors and …, 2021 - Elsevier
As a class of crystalline porous materials, metal-organic frameworks (MOFs) have attracted
increasing attention. Due to the nanoscale framework structure, adjustable pore size, large …

Dependence of nanoparticle toxicity on their physical and chemical properties

A Sukhanova, S Bozrova, P Sokolov… - Nanoscale research …, 2018 - Springer
Studies on the methods of nanoparticle (NP) synthesis, analysis of their characteristics, and
exploration of new fields of their applications are at the forefront of modern nanotechnology …

Microfluidics for drug development: from synthesis to evaluation

Y Liu, L Sun, H Zhang, L Shang, Y Zhao - Chemical reviews, 2021 - ACS Publications
Drug development is a long process whose main content includes drug synthesis, drug
delivery, and drug evaluation. Compared with conventional drug development procedures …

[HTML][HTML] Application of microfluidic chip technology in pharmaceutical analysis: A review

P Cui, S Wang - Journal of pharmaceutical analysis, 2019 - Elsevier
The development of pharmaceutical analytical methods represents one of the most
significant aspects of drug development. Recent advances in microfabrication and …

Microfluidic devices for drug delivery systems and drug screening

S Damiati, UB Kompella, SA Damiati, R Kodzius - Genes, 2018 - mdpi.com
Microfluidic devices present unique advantages for the development of efficient drug carrier
particles, cell-free protein synthesis systems, and rapid techniques for direct drug screening …

Surface modification techniques for endothelial cell seeding in PDMS microfluidic devices

F Akther, SB Yakob, NT Nguyen, HT Ta - Biosensors, 2020 - mdpi.com
Microfluidic lab-on-a-chip cell culture techniques have been gaining popularity by offering
the possibility of reducing the amount of samples and reagents and greater control over …

Recent advances of controlled drug delivery using microfluidic platforms

ST Sanjay, W Zhou, M Dou, H Tavakoli, L Ma… - Advanced drug delivery …, 2018 - Elsevier
Conventional systematically-administered drugs distribute evenly throughout the body, get
degraded and excreted rapidly while crossing many biological barriers, leaving minimum …

Recent advances on cell culture platforms for in vitro drug screening and cell therapies: from conventional to microfluidic strategies

BD Cardoso, EMS Castanheira… - Advanced …, 2023 - Wiley Online Library
The clinical translations of drugs and nanomedicines depend on coherent pharmaceutical
research based on biologically accurate screening approaches. Since establishing the 2D in …

Spheroids-on-a-chip: Recent advances and design considerations in microfluidic platforms for spheroid formation and culture

K Moshksayan, N Kashaninejad, ME Warkiani… - Sensors and Actuators B …, 2018 - Elsevier
A cell spheroid is a three-dimensional (3D) aggregation of cells. Synthetic, in-vitro spheroids
provide similar metabolism, proliferation, and species concentration gradients to those found …

Engineering microfluidic organoid-on-a-chip platforms

F Yu, W Hunziker, D Choudhury - Micromachines, 2019 - mdpi.com
In vitro cell culture models are emerging as promising tools to understand human
development, disease progression, and provide reliable, rapid and cost-effective results for …