Safe sequencing system

B Vogelstein, KW Kinzler, N Papadopoulos… - US Patent …, 2021 - Google Patents
Though massively parallel sequencing instruments are in principle well-suited to the task of
identification of mutations present in a small fraction of DNA templates, the error rates in …

Assaying ovarian cyst fluid

Y Wang, B Vogelstein, KW Kinzler, L Diaz… - US Patent …, 2022 - Google Patents
A diagnostic test for ovarian cysts is based on the detection of mutations characteristic of the
most common neoplasms giving rise to these lesions. With this test, tumor-specific mutations …

Safe sequencing system

B Vogelstein, KW Kinzler, N Papadopoulos… - US Patent …, 2022 - Google Patents
The identification of mutations that are present in a small fraction of DNA templates is
essential for progress in several areas of biomedical research. Though massively parallel …

Safe sequencing system

B Vogelstein, KW Kinzler, N Papadopoulos… - US Patent …, 2024 - Google Patents
The identification of mutations that are present in a small fraction of DNA templates is
essential for progress in several areas of biomedical research. Though massively parallel …

Safe sequencing system

B Vogelstein, KW Kinzler, N Papadopoulos… - US Patent …, 2023 - Google Patents
The identification of mutations that are present in a small fraction of DNA templates is
essential for progress in several areas of biomedical research. Though massively parallel …

Methods of producing nucleic acid libraries and compositions and kits for practicing same

R Green, J Kapp - US Patent 11,629,345, 2023 - Google Patents
2021-07-22 Assigned to THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
reassignment THE REGENTS OF THE UNIVERSITY OF CALIFORNIA ASSIGNMENT OF …

Methods of Amplifying Nucleic Acids and Compositions and Kits for Practicing the Same

T Kazuo - US Patent App. 16/963,365, 2021 - Google Patents
Methods of amplifying nucleic acids in a sample are provided. Aspects of the methods
include: a) fragment ing nucleic acids in the sample to produce a fragmented nucleic acid …

Integrative DNA and RNA Library Preparations and Uses Thereof

Y Wang, Q Peng, D Kim - US Patent App. 17/041,724, 2021 - Google Patents
The invention relates to integrated DNA and RNA library preparations and methods of
making and uses thereof, wherein the DNA molecules are labelled with a tag identi fying the …

Safe sequencing system

B Vogelstein, KW Kinzler, N Papadopoulos… - US Patent …, 2022 - Google Patents
The identification of mutations that are present in a small fraction of DNA templates is
essential for progress in several areas of biomedical research. Though massively parallel …

Differential tagging of RNA for preparation of a cell-free DNA/RNA sequencing library

M Larson, HJ Kim, N Eattock, A Jamshidi - US Patent 11,180,801, 2021 - Google Patents
In various aspects, the present disclosure provides methods, compositions, reactions
mixtures, kits, and systems for sequencing both RNA and DNA from a single source sample …