The protein isoelectric point (pI) can be calculated from an amino acid sequence using
computational analysis in a good agreement with experimental data. Availability of whole …

Background Accurate estimation of the isoelectric point (pI) based on the amino acid
sequence is useful for many analytical biochemistry and proteomics techniques such as 2-D …

The isoelectric point is the pH at which a particular molecule is electrically neutral due to the
equilibrium of positive and negative charges. In proteins and peptides, this depends on the …

Proteome-pI is an online database containing information about predicted isoelectric points
for 5029 proteomes calculated using 18 methods. The isoelectric point, the pH at which a …

The review brings a comprehensive overview of recent developments and applications of
high performance capillary and microchip electroseparation methods (zone electrophoresis …

Motivation: In any macromolecular polyprotic system—for example protein, DNA or RNA—
the isoelectric point—commonly referred to as the p I—can be defined as the point of …

Posttranslational modifications of proteins play fundamental roles in protein function in
health and disease. More than 600 different types of posttranslational modifications are …

Electrostatic interactions play essential roles in determining the function, colloidal stability,
and adsorption of proteins on different surfaces and interfaces. Therefore, a molecular-level …

Lassa mammarenavirus (LASMV) is responsible for a specific type of acute viral
hemorrhagic fever known as Lassa fever. Lack of effective treatments and counter-measures …

Abstract Summary p K a values of ionizable residues and isoelectric points of proteins
provide valuable local and global insights about their structure and function. These …