Infections with protozoan parasites are a major cause of disease and mortality in many
tropical countries of the world. Diseases caused by species of the genera Trypanosoma …

Plants are phytochemical hubs containing antioxidants, essential for normal plant
functioning and adaptation to environmental cues and delivering beneficial properties for …

The development of one-pot imine formation and asymmetric Pictet− Spengler reactions
cocatalyzed by a chiral thiourea and benzoic acid is described. Optically active tetrahydro-β …

The Amaryllidaceae alkaloids represent a large (over 300 alkaloids have been isolated) and
still expanding group of biogenetically related isoquinoline alkaloids that are found …

Alkaloids are an important group of specialized nitrogen metabolites with a wide range of
biochemical and pharmacological effects. Since the first publication on lycorine in 1877 …

Aims Amaryllidaceae alkaloids exhibit a wide range of physiological effects, of which the
acetylcholinesterase (AChE) inhibitory activity is the most relevant. However, scientific …

Leishmaniasis is a clinical manifestation caused by the parasites of the genus Leishmania.
Plants are reservoirs of bioactive compounds, which are known to be chemically balanced …

Podophyllotoxin is a naturally occurring cyclolignan isolated from rhizomes of Podophyllum
sp. In the clinic, it is used mainly as an antiviral; however, its antitumor activity is even more …

Acetylcholinesterase (AChE) enzymatic inhibition is an important target for the management
of Alzheimer disease (AD) and AChE inhibitors are the mainstay drugs for its treatment. In …

Cinchona alkaloids comprising quinine, quinidine, cinchonidine, and cinchonine as the
major members constitute a unique class of quinoline alkaloids with tremendous impact on …