[HTML][HTML] Cancer chemotherapy and beyond: Current status, drug candidates, associated risks and progress in targeted therapeutics
U Anand, A Dey, AKS Chandel, R Sanyal, A Mishra… - Genes & …, 2023 - Elsevier
Cancer is an abnormal state of cells where they undergo uncontrolled proliferation and
produce aggressive malignancies that causes millions of deaths every year. With the new …
produce aggressive malignancies that causes millions of deaths every year. With the new …
Regulation and signaling pathways in cancer stem cells: implications for targeted therapy for cancer
Z Zeng, M Fu, Y Hu, Y Wei, X Wei, M Luo - Molecular Cancer, 2023 - Springer
Cancer stem cells (CSCs), initially identified in leukemia in 1994, constitute a distinct subset
of tumor cells characterized by surface markers such as CD133, CD44, and ALDH. Their …
of tumor cells characterized by surface markers such as CD133, CD44, and ALDH. Their …
Nanog, as a key cancer stem cell marker in tumor progression
Cancer stem cells (CSCs) are a small population of malignant cells that induce tumor onset
and development. CSCs share similar features with normal stem cells in the case of self …
and development. CSCs share similar features with normal stem cells in the case of self …
Understanding the role of the transcription factor Sp1 in ovarian cancer: from theory to practice
B Vellingiri, M Iyer, M Devi Subramaniam… - International journal of …, 2020 - mdpi.com
Ovarian cancer (OC) is one of the deadliest cancers among women contributing to high risk
of mortality, mainly owing to delayed detection. There is no specific biomarker for its …
of mortality, mainly owing to delayed detection. There is no specific biomarker for its …
NANOG decoy oligodeoxynucleotide–encapsulated niosomes nanocarriers: a promising approach to suppress the metastatic properties of U87 human glioblastoma …
M Gharbavi, B Johari, E Rismani… - ACS Chemical …, 2020 - ACS Publications
Recently, advances in the synthesis and development of multifunctional nanoparticle
platforms have opened up great opportunities and advantages for specifically targeted …
platforms have opened up great opportunities and advantages for specifically targeted …
CircMEG3 inhibits telomerase activity by reducing Cbf5 in human liver cancer stem cells
X Jiang, L Xing, Y Chen, R Qin, S Song, Y Lu… - … Therapy-Nucleic Acids, 2021 - cell.com
Circular RNA (CircRNA) is a newly identified special class of non-coding RNA (ncRNA) that
plays an important regulatory role in the progression of certain diseases. Herein, our results …
plays an important regulatory role in the progression of certain diseases. Herein, our results …
PTEN/AKT/mTOR signaling mediates anticancer effects of epigallocatechin‑3‑gallate in ovarian cancer
J Qin, M Fu, J Wang, F Huang, H Liu… - Oncology …, 2020 - spandidos-publications.com
Abstract Epigallocatechin‑3‑gallate (EGCG), a polyphenol present in green tea, exhibits
anticancer effects in various types of cancer. A number of studies have focused on the …
anticancer effects in various types of cancer. A number of studies have focused on the …
Dual role of quercetin in enhancing the efficacy of cisplatin in chemotherapy and protection against its side effects: a review
Chemotherapy has opened a new window in cancer therapy. However, the resistance of
cancer cells has dramatically reduced the efficacy of chemotherapy. Cisplatin is a …
cancer cells has dramatically reduced the efficacy of chemotherapy. Cisplatin is a …
Expression patterns and clinical significance of the potential cancer stem cell markers OCT4 and NANOG in colorectal cancer patients
Colorectal cancer (CRC) is one of the most important malignancies and causes of cancer-
related deaths worldwide. Cancer stem cell markers identification could be helpful to acquire …
related deaths worldwide. Cancer stem cell markers identification could be helpful to acquire …
NANOG promotes cell proliferation, invasion, and stemness via IL-6/STAT3 signaling in esophageal squamous carcinoma
L Deng, X Zhang, X Xiang, R Xiong… - … in cancer research …, 2021 - journals.sagepub.com
Background: Cancer cells have properties similar to those of stem cells, including high
proliferation and self-renewal ability. NANOG is the key regulatory gene that maintains the …
proliferation and self-renewal ability. NANOG is the key regulatory gene that maintains the …