Among gynecologic malignancies, ovarian cancer is one of the most dangerous, with a high
fatality rate and relapse due to the occurrence of chemoresistance. Many researchers …

Abstract 17β‐Estradiol (E2), as the main circulating estrogen hormone, regulates many
tissue and organ functions in physiology. The effects of E2 on cells are mediated by the …

Soyfoods have long been recognized as sources of high-quality protein and healthful fat, but
over the past 25 years these foods have been rigorously investigated for their role in chronic …

Estrogen receptor alpha (ERα) has been recognized now for several decades as playing a
key role in reproduction and exerting functions in numerous nonreproductive tissues. In this …

Phytoestrogens are literally estrogenic substances of plant origin. Although these
substances are useful for plants in many aspects, their estrogenic properties are essentially …

Cancer is a major public health concern in both developed and developing countries.
Several plant-derived anti-cancer agents including taxol, vinblastine, vincristine, the …

Polyphenols and consequently many flavonoids have several beneficial actions on human
health. However, the actual molecular interactions of polyphenols with biological systems …

Advances in the flavonoid field have been nothing short of spectacular over the last 20
years. While the medical field has noticed flavonoids for their potential antioxidant …

During the past decade there has been a substantial advance in our understanding of
estrogen signaling both from a clinical as well as a preclinical perspective. Estrogen …

Our appreciation of the physiological functions of estrogens and the mechanisms through
which estrogens bring about these functions has changed during the past decade. Just as …