[HTML][HTML] Recent drug design strategies and identification of key heterocyclic scaffolds for promising anticancer targets
Cancer, a noncommunicable disease, is the leading cause of mortality worldwide and is
anticipated to rise by 75% in the next two decades, reaching approximately 25 million cases …
anticipated to rise by 75% in the next two decades, reaching approximately 25 million cases …
[HTML][HTML] A recent update on the environment friendly methodologies to synthesize bis (indolyl) methane and 3, 3-di (3-indolyl)-2-indolone derivatives
Indole, widely recognized as a versatile category of heterocyclic frameworks that contain
nitrogen is extensively employed in the synthesis of various organic compounds due to their …
nitrogen is extensively employed in the synthesis of various organic compounds due to their …
Recent advances in cascade reactions and their mechanistic insights: a concise strategy to synthesize complex natural products and organic scaffolds
G Tiwari, M Kumar, ANS Chauhan… - Organic & Biomolecular …, 2022 - pubs.rsc.org
The beauty of cascade reactions to bestow us with cumbersome organic scaffolds has made
them a cutting-edge area of research. Although the planning of cascades may require …
them a cutting-edge area of research. Although the planning of cascades may require …
Advances in organocatalyzed synthesis of organic compounds
The recent advancements in utilizing organocatalysts for the synthesis of organic
compounds have been described in this review by focusing on their simplicity, effectiveness …
compounds have been described in this review by focusing on their simplicity, effectiveness …
Synthesis, characterization, and antibacterial activity of novel bis (indolyl) methanes sourced from biorenewable furfurals using gluconic acid aqueous solution (GAAS) …
Bis (indolyl) methanes (BIMs) are important heterocycle-containing molecular scaffolds that
show remarkable biological and pharmacological activities. This work reports the synthesis …
show remarkable biological and pharmacological activities. This work reports the synthesis …
Increased catalytic activity through ZnMo7O24/gC3N4 heterostructured assemblies for greener indole condensation reaction at room temperature
As an economical conjugated polymer, graphitic carbon nitride (g-C3N4) has recently
attracted much attention due to its exciting chemical and thermal stability and easy …
attracted much attention due to its exciting chemical and thermal stability and easy …
[RhCp*Cl2]2-Catalyzed Indole Functionalization: Synthesis of Bioinspired Indole-Fused Polycycles
AN Singh Chauhan, G Mali, G Dua, P Samant… - ACS …, 2023 - ACS Publications
Polycyclic fused indoles are ubiquitous in natural products and pharmaceuticals due to their
immense structural diversity and biological inference, making them suitable for charting …
immense structural diversity and biological inference, making them suitable for charting …
Transition metal-free efficient synthesis of bis (indolyl) propynes (BIPs)
A Chaturvedi, V Sharma, F Nafla… - Organic & …, 2024 - pubs.rsc.org
A transition metal-free approach has been devised for the synthesis of a variety of bis
(indolyl) propyne (BIP) derivatives. The strategy involves an iodine-catalyzed cascade …
(indolyl) propyne (BIP) derivatives. The strategy involves an iodine-catalyzed cascade …
Effective Synthesis and Biological Evaluation of Functionalized 2,3-Dihydrofuro[3,2-c]coumarins via an Imidazole-Catalyzed Green Multicomponent Approach
For the first time, an eco-friendly and efficient one-pot green multicomponent approach has
been described to synthesize functionalized trans-2, 3-dihydrofuro [3, 2-c] coumarins …
been described to synthesize functionalized trans-2, 3-dihydrofuro [3, 2-c] coumarins …
Mitotic Functions and Characters of KIF11 in Cancers
W Gao, J Lu, Z Yang, E Li, Y Cao, L Xie - Biomolecules, 2024 - mdpi.com
Mitosis mediates the accurate separation of daughter cells, and abnormalities are closely
related to cancer progression. KIF11, a member of the kinesin family, plays a vital role in the …
related to cancer progression. KIF11, a member of the kinesin family, plays a vital role in the …