Cognitive dysfunction in non-alcoholic fatty liver disease—current knowledge, mechanisms and perspectives
K Kjærgaard, ACD Mikkelsen, CW Wernberg… - Journal of Clinical …, 2021 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) has emerged as the hepatic component of the
metabolic syndrome and now seemingly affects one-fourth of the world population. Features …
metabolic syndrome and now seemingly affects one-fourth of the world population. Features …
[HTML][HTML] Lipocalin 2 as a link between ageing, risk factor conditions and age-related brain diseases
DW Dekens, ULM Eisel, L Gouweleeuw… - Ageing research …, 2021 - Elsevier
Chronic (neuro) inflammation plays an important role in many age-related central nervous
system (CNS) diseases, including Alzheimer's disease, Parkinson's disease and vascular …
system (CNS) diseases, including Alzheimer's disease, Parkinson's disease and vascular …
Oxidative stress mediated by the TLR4/NOX2 signalling axis is involved in polystyrene microplastic-induced uterine fibrosis in mice
H Wu, T Xu, T Chen, J Liu, S Xu - Science of the Total Environment, 2022 - Elsevier
Microplastics (MPs), as a new environmental pollutant, have received widespread attention
worldwide. Uterine fibrosis is one of the main factors of female reproductive disorders …
worldwide. Uterine fibrosis is one of the main factors of female reproductive disorders …
Glioma-derived exosomes hijack the blood–brain barrier to facilitate nanocapsule delivery via LCN2
C Yang, Y Wu, L Wang, S Li, J Zhou, Y Tan… - Journal of Controlled …, 2022 - Elsevier
Exosomes are small extracellular vehicles which could transport genetic materials and
proteins between cells. Although there are reports about exosomes crossing the blood-brain …
proteins between cells. Although there are reports about exosomes crossing the blood-brain …
The role of intestinal bacteria and gut–brain axis in hepatic encephalopathy
Z Chen, J Ruan, D Li, M Wang, Z Han… - Frontiers in Cellular …, 2021 - frontiersin.org
Hepatic encephalopathy (HE) is a neurological disorder that occurs in patients with liver
insufficiency. However, its pathogenesis has not been fully elucidated. Pharmacotherapy is …
insufficiency. However, its pathogenesis has not been fully elucidated. Pharmacotherapy is …
[HTML][HTML] Association of non-alcoholic fatty liver disease with incident dementia later in life among elder adults
Methods The study population included 608,994 adults aged≥ 60 years who underwent
health examinations between 2009 and 2010. Data were collected from the Korean National …
health examinations between 2009 and 2010. Data were collected from the Korean National …
Lipocalin‐2 activates hepatic stellate cells and promotes nonalcoholic steatohepatitis in high‐fat diet–fed Ob/Ob mice
KE Kim, J Lee, HJ Shin, EA Jeong, HM Jang, YJ Ahn… - Hepatology, 2023 - journals.lww.com
Lipocalin‐2 activates hepatic stellate cells and promotes no... : Hepatology Lipocalin‐2
activates hepatic stellate cells and promotes nonalcoholic steatohepatitis in high‐fat diet–fed …
activates hepatic stellate cells and promotes nonalcoholic steatohepatitis in high‐fat diet–fed …
TNFα-induced NLRP3 inflammasome mediates adipocyte dysfunction and activates macrophages through adipocyte-derived lipocalin 2
HMA Javaid, E Ko, EJ Joo, SH Kwon, JH Park, S Shin… - Metabolism, 2023 - Elsevier
Background and aims Obesity is a state of chronic low-grade systemic inflammation. Recent
studies showed that NLRP3 inflammasome initiates metabolic dysregulation in adipose …
studies showed that NLRP3 inflammasome initiates metabolic dysregulation in adipose …
Lipocalin-2-mediated astrocyte pyroptosis promotes neuroinflammatory injury via NLRP3 inflammasome activation in cerebral ischemia/reperfusion injury
J Li, P Xu, Y Hong, Y Xie, M Peng, R Sun… - Journal of …, 2023 - Springer
Background Neuroinflammation is a vital pathophysiological process during ischemic stroke.
Activated astrocytes play a major role in inflammation. Lipocalin-2 (LCN2), secreted by …
Activated astrocytes play a major role in inflammation. Lipocalin-2 (LCN2), secreted by …
Influence of cardiometabolic comorbidities on myocardial function, infarction, and cardioprotection: Role of cardiac redox signaling
The morbidity and mortality from cardiovascular diseases (CVD) remain high. Metabolic
diseases such as obesity, hyperlipidemia, diabetes mellitus (DM), non-alcoholic fatty liver …
diseases such as obesity, hyperlipidemia, diabetes mellitus (DM), non-alcoholic fatty liver …