Environmental benign RP-HPLC method for the simultaneous estimation of anti-hypertensive drugs using analytical quality by design

N Dharuman, KS Lakshmi… - Green Chemistry Letters …, 2023 - Taylor & Francis
Green analytical procedures replace harmful organic modifiers with green solvents without
affecting chromatographic performance, enabling industries and research laboratories to …

A robust high-performance thin-layer chromatography method for the simultaneous estimation of chlorthalidone and metoprolol succinate using quality risk …

P Prajapati, M Patel, S Shah - JPC–Journal of Planar Chromatography …, 2021 - Springer
A precise, robust and accurate high-performance thin-layer chromatography (HPTLC)
method has been developed for the simultaneous estimation of chlorthalidone and …

Mathematically processed UV spectroscopic method for quantification of chlorthalidone and azelnidipine in bulk and formulation: evaluation of greenness and …

M Attimarad, MS Chohan… - Journal of …, 2022 - Wiley Online Library
A simple, eco‐friendly four analytical methods were established by improving the selectivity
through the application of mathematical processing of UV absorption spectra for concurrent …

[HTML][HTML] A concise review on analytical profile of chlorthalidone

YA Chaudhari, VR Patil, RR Gujar, KR Patil… - Research Journal of …, 2022 - rjpdft.com
Chlorthalidone (CHL) is an anti-hypertensive that reduces active sodium reabsorption and
peripheral vascular resistance. Also, it is a diuretic commonly known as a thiazide diuretic …

Analytical Quality by Design Approach of Reverse‐Phase High‐Performance Liquid Chromatography of Atorvastatin: Method Development, Optimization, Validation …

NK Alruwaili - International Journal of Analytical Chemistry, 2021 - Wiley Online Library
The use of analytical quality by design (AQbD) approach in the optimization of the high‐
performance liquid chromatography (RP‐HPLC) method is a novel tool. Three factors and …

[HTML][HTML] Eco-friendly based HPLC and UV-spectrophotometric methods for simultaneous estimation of Efonidipine hydrochloride Ethanolate and Chlorthalidone in …

H Darji, Z Dedania, R Dedania, V Jain - Green Analytical Chemistry, 2024 - Elsevier
Abstract Objective Efonidipine hydrochloride Ethanolate and Chlorthalidone combination
was approved by CDSCO for Phase III clinical trial. This combination is utilized to …

A Validated RP‐HPLC Stability Method for the Estimation of Chlorthalidone and Its Process‐Related Impurities in an API and Tablet Formulation

C Kharat, VA Shirsat, YM Kodgule… - International Journal of …, 2020 - Wiley Online Library
Low‐dose thiazide and thiazide‐like diuretics are widely used as first‐line therapy for
hypertension. Chlorthalidone, a monosulfamyl diuretic, is frequently prescribed in cases of …

[HTML][HTML] Development of Personalised Immediate-Release Gel-Based Formulations Using Semi-Solid Extrusion

M Aina, F Baillon, R Sescousse, NM Sanchez-Ballester… - Gels, 2024 - mdpi.com
Precision in dosing is crucial for optimizing therapeutic outcomes and preventing
overdosing, especially in preterm infants. Traditional manual adjustments to adapt the dose …

Development and validation of a stability indicating RP-HPLC method for the estimation of chlorthalidone and cilnidipine in combined pharmaceutical dosage form

L Sawaikar, P Kapupara - Research Journal of Pharmacy and …, 2020 - indianjournals.com
A simple and a rapid stability indicating RP-HPLC method has been developed for the
estimation of Chlorthalidone and Cilnidipine in their combined dosage form. The separation …

[PDF][PDF] Bioanalytical method development and validation for simultaneous determination of chlorthalidone and cilnidipine drugs in human plasma by RP-HPLC

MM Eswarudu, AL Rao, K Vijay - International journal of research in …, 2019 - academia.edu
ABSTRACT A simple, rapid, sensitive, precise and accurate high performance liquid
chromatography method was developed for simultaneous determination of Chlorthalidone …