Periodontitis is an inflammatory disease of oxidative stress: We should treat it that way

FSC Sczepanik, ML Grossi, M Casati… - Periodontology …, 2020 - Wiley Online Library
Periodontitis is a highly prevalent disease. As it progresses, it causes serious morbidity in
the form of periodontal abscesses and tooth loss and, in the latter stages, pain. It is also now …

Oxidative stress and antioxidant system in periodontitis

Y Wang, O Andrukhov, X Rausch-Fan - Frontiers in physiology, 2017 - frontiersin.org
Periodontitis is a common inflammatory disease, which is initiated by bacterial infection and
subsequently progressed by aberrant host response. It can result in the destruction of teeth …

Oxidative stress‐related biomarkers in saliva and gingival crevicular fluid associated with chronic periodontitis: A systematic review and meta‐analysis

M Chen, W Cai, S Zhao, L Shi, Y Chen… - Journal of clinical …, 2019 - Wiley Online Library
Aim Oxidative stress (OS) biomarkers have been detected in saliva and gingival crevicular
fluid (GCF) during chronic periodontitis (CP) progression; however, the relationship between …

Oxidative stress and antioxidants in the diagnosis and therapy of periodontitis

L Tóthová, P Celec - Frontiers in physiology, 2017 - frontiersin.org
Oxidative stress has been implicated in the pathogenesis of numerous diseases. However,
large interventional studies with antioxidants failed to show benefits in the prevention or …

Lipid peroxidation levels and total oxidant/antioxidant status in serum and saliva from patients with chronic and aggressive periodontitis. Oxidative stress index: a new …

E Baltacıoğlu, P Yuva, G Aydın, A Alver… - Journal of …, 2014 - Wiley Online Library
Background: In this study, levels of malondialdehyde (MDA), which is a significant product of
lipid peroxidation (LPO), total oxidant status (TOS), total antioxidant capacity (TAOC), and …

Tobacco use and periodontal disease—the role of microvascular dysfunction

H Silva - Biology, 2021 - mdpi.com
Simple Summary Periodontal disease consists of a wide range of inflammatory conditions
that affect the supporting apparatus of teeth, and is highly prevalent in adults worldwide …

LPS from P. gingivalis and Hypoxia Increases Oxidative Stress in Periodontal Ligament Fibroblasts and Contributes to Periodontitis

L Gölz, S Memmert, B Rath-Deschner… - Mediators of …, 2014 - Wiley Online Library
Oxidative stress is characterized by an accumulation of reactive oxygen species (ROS) and
plays a key role in the progression of inflammatory diseases. We hypothesize that hypoxic …

Assessment of oxidative stress by the estimation of lipid peroxidation marker malondialdehyde (MDA) in patients with chronic periodontitis: a systematic review and …

K Mohideen, K Chandrasekar… - … Journal of Dentistry, 2023 - Wiley Online Library
Objective. The present systematic review and meta‐analysis aimed to assess the oxidative
stress‐mediated lipid peroxidation end product malondialdehyde (MDA) in periodontitis …

Metabolomics of gingival crevicular fluid to identify biomarkers for periodontitis: a systematic review with meta‐analysis

G Baima, M Corana, G Iaderosa… - Journal of …, 2021 - Wiley Online Library
The present systematic review aimed to examine periodontitis‐specific biomarkers in the
gingival crevicular fluid (GCF) that could have a diagnostic relevance, and to provide a …

Evaluation of antioxidant enzymes activity and malondialdehyde levels in patients with chronic periodontitis and diabetes mellitus

S Trivedi, N Lal, AA Mahdi, M Mittal… - Journal of …, 2014 - Wiley Online Library
Background: The aim of this study is to investigate the impact of diabetes, a known risk factor
for periodontitis, on activities of antioxidant enzymes superoxide dismutase (SOD) …