In mammals, environmental sounds stimulate the auditory receptor, the cochlea, via
vibrations of the stapes, the innermost of the middle ear ossicles. These vibrations produce …

This review covers the basic anatomy and physiology of the olivocochlear reflexes and the
use of otoacoustic emissions (OAEs) in humans to monitor the effects of one group, the …

The classic view of sensorineural hearing loss (SNHL) is that the “primary” targets are hair
cells, and that cochlear-nerve loss is “secondary” to hair cell degeneration. Our recent work …

We report the cloning and characterization of rat α10, a previously unidentified member of
the nicotinic acetylcholine receptor (nAChR) subunit gene family. The protein encoded by …

The anatomy and physiology of olivocochlear (OC) efferents are reviewed. To help interpret
these, recent advances in cochlear mechanics are also reviewed. Lateral OC (LOC) …

The availability of transgenic and mutant lines makes the mouse a valuable model for study
of the inner ear, and a powerful window into cochlear function can be obtained by …

Although protective effects of the cochlea's efferent feedback pathways have been well
documented, prior work has focused on hair cell damage and cochlear threshold elevation …

The inner ear receives two types of efferent feedback from the brainstem: one pathway
provides gain control on outer hair cells' contribution to cochlear amplification, and the other …

Auditory neurons must represent accurately a wide range of sound levels using firing rates
that vary over a far narrower range of levels. Recently, we demonstrated that this “dynamic …

Medial olivocochlear efferent (MOCE) neurones innervate the outer hair cells (OHCs) of the
mammalian cochlea, and convey signals that are capable of controlling the sensitivity of the …