Phytochemical constituents as future antidepressants: a comprehensive review

R Bahramsoltani, MH Farzaei, MS Farahani… - Reviews in the …, 2015 - degruyter.com
Depression is a major mental disease that is ranked as the fourth leading cause of disability.
In order to avoid unwanted adverse reactions, as well as improve efficacy, current …

[HTML][HTML] The application of metabolomics in investigating anti-diabetic activity of medicinal plants

M Hasanpour, M Iranshahy, M Iranshahi - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Diabetes mellitus is the most prevalent endocrine disease in the world and is likely to be the
major epidemic in human history. In current years, many modern anti-diabetic medicines …

Antidepressant‐Like Effects of Gyejibokryeong-hwan in a Mouse Model of Reserpine‐Induced Depression

BK Park, YR Kim, YH Kim, C Yang… - BioMed research …, 2018 - Wiley Online Library
Treatment with the antihypertensive agent reserpine depletes monoamine levels, resulting
in depression. In the present study, we evaluated the antidepressant effects of …

Fructus Gardenia (Gardenia jasminoides J. Ellis) phytochemistry, pharmacology of cardiovascular, and safety with the perspective of new drugs development

H Liu, YF Chen, F Li, HY Zhang - Journal of Asian Natural Products …, 2013 - Taylor & Francis
The phytochemistry, cardiovascular pharmacology, toxicology, side effect, and further
development prospects of Gardenia jasminoides J. Ellis (GJE) and its main constituents …

Antidepressant and anti-neuroinflammatory effects of Bangpungtongsung-San

BK Park, NS Kim, YR Kim, C Yang, IC Jung… - Frontiers in …, 2020 - frontiersin.org
Bangpungtongsung-san (BTS) is a traditional Korean medicine consisting of 18 herbs, some
which have antidepressant effects. Here, we used an animal model of reserpine-induced …

1H-NMR-Based Metabonomic Studies on the Anti-Depressant Effect of Genipin in the Chronic Unpredictable Mild Stress Rat Model

JS Tian, BY Shi, H Xiang, S Gao, XM Qin, GH Du - PloS one, 2013 - journals.plos.org
The purpose of this work was to investigate the anti-depressant effect of genipin and its
mechanisms using 1H-NMR spectroscopy and multivariate data analysis on a chronic …

Genipin prevents alpha-synuclein aggregation and toxicity by affecting endocytosis, metabolism and lipid storage

R Rosado-Ramos, GM Poças, D Marques… - Nature …, 2023 - nature.com
Parkinson's Disease (PD) is a common neurodegenerative disorder affecting millions of
people worldwide for which there are only symptomatic therapies. Small molecules able to …

A review through recovery, purification and identification of genipin

AM Ramos-de-la-Peña, CMGC Renard… - Phytochemistry …, 2016 - Springer
Genipin is a secoiridoid that may be obtained directly from Genipa americana and after
geniposide hydrolysis from Gardenia jasminoides fruits. It is well known that genipin is a …

Antidepressant-like effects of the Radix Bupleuri and Radix Paeoniae Alba drug pair

Y Wang, SM Gao, R Li, M Zhang, S Gao, CQ Yu - Neuroscience letters, 2016 - Elsevier
Abstract The Radix Bupleuri and Radix Paeoniae Alba drug pair plays a pivotal role in
Xiaoyaosan, a famous Chinese herbal preparation that is popular in clinical medicine. To …

Therapeutic potential of genipin in central neurodegenerative diseases

Y Li, L Li, C Hölscher - CNS drugs, 2016 - Springer
Central neurodegenerative diseases, such as Alzheimer's disease (AD) and Parkinson's
disease (PD), are one of the biggest health problems worldwide. Currently, there is no cure …