What turns CREB on? And off? And why does it matter?
A Steven, M Friedrich, P Jank, N Heimer… - Cellular and Molecular …, 2020 - Springer
Altered expression and function of the transcription factor cyclic AMP response-binding
protein (CREB) has been identified to play an important role in cancer and is associated with …
protein (CREB) has been identified to play an important role in cancer and is associated with …
Role of microRNAs in the development, prognosis and therapeutic response of patients with prostate cancer
Prostate cancer is the most common cancer in males in several regions. One of the major
challenges in diagnosis and treatment of this cancer is how to identify men who harbor an …
challenges in diagnosis and treatment of this cancer is how to identify men who harbor an …
Decreased miR-200b-3p in cancer cells leads to angiogenesis in HCC by enhancing endothelial ERG expression
A Moh-Moh-Aung, M Fujisawa, S Ito, H Katayama… - Scientific reports, 2020 - nature.com
Transcription factor ERG (erythroblast transformation-specific (ETS)-related gene) is
essential in endothelial differentiation and angiogenesis, in which microRNA (miR)-200b-3p …
essential in endothelial differentiation and angiogenesis, in which microRNA (miR)-200b-3p …
Circular RNA ABCB10 correlates with advanced clinicopathological features and unfavorable survival, and promotes cell proliferation while reduces cell apoptosis in …
Y Chen, X Ye, X Xia, X Lin - Cancer Biomarkers, 2019 - content.iospress.com
OBJECTIVE: This study aimed to explore the correlation of circular RNA ABCB10 (circ-
ABCB10) expression with clinicopathological features and survival, as well as its impact on …
ABCB10) expression with clinicopathological features and survival, as well as its impact on …
Circ_0011373 promotes papillary thyroid carcinoma progression by regulating miR-1271/LRP6 axis
G Huang, L Mao, X Hu - Hormones, 2023 - Springer
Purpose This research aimed to explore the regulatory molecular mechanism among
circular RNA (circ) _0011373, microRNA (miR)-1271, and lipoprotein receptor-related …
circular RNA (circ) _0011373, microRNA (miR)-1271, and lipoprotein receptor-related …
Downregulation of lncRNA UCA1 facilitates apoptosis and reduces proliferation in multiple myeloma via regulation of the miR-1271-5p/HGF axis
Y Yang, L Chen - Journal of the Chinese Medical Association, 2019 - journals.lww.com
Background: Long noncoding RNAs (lncRNAs) are considered to be a novel prognostic and
therapeutic target in many cancers. This study identified dysregulation of lncRNA urothelial …
therapeutic target in many cancers. This study identified dysregulation of lncRNA urothelial …
Emodin: A metabolite that exhibits anti-neoplastic activities by modulating multiple oncogenic targets
Oncogenic transformation has been the major cause of global mortality since decades.
Despite established therapeutic regimes, majority of cancer patients either present with …
Despite established therapeutic regimes, majority of cancer patients either present with …
Estrogen receptor-α-miR-1271-SNAI2 feedback loop regulates transforming growth factor-β-induced breast cancer progression
BW Liu, ZH Yu, AX Chen, JR Chi, J Ge, Y Yu… - Journal of Experimental …, 2019 - Springer
Background Breast cancer is the most common cancer among women worldwide, and
approximately 70% of breast cancers are hormone receptor-positive and express estrogen …
approximately 70% of breast cancers are hormone receptor-positive and express estrogen …
[PDF][PDF] MiR-1271 negatively regulates AKT/MTOR signaling and promotes apoptosis via targeting PDK1 in pancreatic cancer.
F Xie, Q Huang, CH Liu, XS Lin, Z Liu… - European Review for …, 2018 - europeanreview.org
OBJECTIVE: Pancreatic cancer (PC) possesses a very poor prognosis, and its pathogenesis
is not fully understood. Evidence has suggested that microRNAs play important roles in …
is not fully understood. Evidence has suggested that microRNAs play important roles in …
[HTML][HTML] The interaction between ETS transcription factor family members and microRNAs: a novel approach to cancer therapy
L Du, Y Liu, C Li, J Deng, Y Sang - Biomedicine & Pharmacotherapy, 2022 - Elsevier
In cancer biology, ETS transcription factors promote tumorigenesis by mediating
transcriptional regulation of numerous genes via the conserved ETS DNA-binding domain …
transcriptional regulation of numerous genes via the conserved ETS DNA-binding domain …