De novo domestication: an alternative route toward new crops for the future

AR Fernie, J Yan - Molecular plant, 2019 - cell.com
Current global agricultural production must feed over 7 billion people. However, productivity
varies greatly across the globe and is under threat from both increased competitions for land …

Metabolomics in the context of plant natural products research: From sample preparation to metabolite analysis

MA Salem, L Perez de Souza, A Serag, AR Fernie… - Metabolites, 2020 - mdpi.com
Plant-derived natural products have long been considered a valuable source of lead
compounds for drug development. Natural extracts are usually composed of hundreds to …

Green giant—a tiny chloroplast genome with mighty power to produce high‐value proteins: history and phylogeny

H Daniell, S Jin, XG Zhu… - Plant biotechnology …, 2021 - Wiley Online Library
Free‐living cyanobacteria were entrapped by eukaryotic cells~ 2 billion years ago, ultimately
giving rise to chloroplasts. After a century of debate, the presence of chloroplast DNA was …

Unraveling plant natural chemical diversity for drug discovery purposes

E Lautié, O Russo, P Ducrot, JA Boutin - Frontiers in pharmacology, 2020 - frontiersin.org
The screening and testing of extracts against a variety of pharmacological targets in order to
benefit from the immense natural chemical diversity is a concern in many laboratories …

The genome of Artemisia annua provides insight into the evolution of Asteraceae family and artemisinin biosynthesis

Q Shen, L Zhang, Z Liao, S Wang, T Yan, PU Shi, M Liu… - Molecular plant, 2018 - cell.com
Artemisia annua, commonly known as sweet wormwood or Qinghao, is a shrub native to
China and has long been used for medicinal purposes. A. annua is now cultivated globally …

Jasmonates are signals in the biosynthesis of secondary metabolites—Pathways, transcription factors and applied aspects—A brief review

C Wasternack, M Strnad - New biotechnology, 2019 - Elsevier
Jasmonates (JAs) are signals in plant stress responses and development. One of the first
observed and prominent responses to JAs is the induction of biosynthesis of different groups …

Synthetic biology of plant natural products: From pathway elucidation to engineered biosynthesis in plant cells

X Zhu, X Liu, T Liu, Y Wang, N Ahmed, Z Li… - Plant Communications, 2021 - cell.com
Plant natural products (PNPs) are the main sources of drugs, food additives, and new
biofuels and have become a hotspot in synthetic biology. In the past two decades, the …

Subcellular compartmentalization in the biosynthesis and engineering of plant natural produces

L Yao, X Wu, X Jiang, M Shan, Z Zhang, Y Li… - Biotechnology …, 2023 - Elsevier
Plant natural products (PNPs) are specialized metabolites with diverse bioactivities. They
are extensively used in the pharmaceutical, cosmeceutical and food industries. PNPs are …

The impact of synthetic biology for future agriculture and nutrition

MS Roell, MD Zurbriggen - Current Opinion in Biotechnology, 2020 - Elsevier
Highlights•Synthetic metabolic pathways to improve plant carbon efficiency.•Reducing
synthetic fertilizer usage in agriculture by optimizing plant nitrogen and phosphorous …

CRISPR-mediated engineering across the central dogma in plant biology for basic research and crop improvement

D Pramanik, RM Shelake, MJ Kim, JY Kim - Molecular Plant, 2021 - cell.com
The central dogma (CD) of molecular biology is the transfer of genetic information from DNA
to RNA to protein. Major CD processes governing genetic flow include the cell cycle, DNA …