Inhibition of insulin degrading enzyme to control diabetes mellitus and its applications on some other chronic disease: A critical review

MS Azam, M Wahiduzzaman… - Pharmaceutical …, 2022 - Springer
Purpose This review aims to provide a precise perceptive of the insulin-degrading enzyme
(IDE) and its relationship to type 2 diabetes (T2D), Alzheimer's disease (AD), obesity, and …

rAAV manufacturing: the challenges of soft sensing during upstream processing

CF Iglesias Jr, M Ristovski, M Bolic, M Cuperlovic-Culf - Bioengineering, 2023 - mdpi.com
Recombinant adeno-associated virus (rAAV) is the most effective viral vector technology for
directly translating the genomic revolution into medicinal therapies. However, the …

[HTML][HTML] Histone deacetylase (HDAC) inhibitor curcumin upregulates mitochondrial uncoupling protein1 (UCP1) and mitochondrial function in brown adipocytes, in …

M Reyad-ul-Ferdous, Y Song, H Zhang… - Journal of Saudi …, 2022 - Elsevier
Mitochondrial dysfunction has been associated with diverse pathological conditions
globally. Specifically, in adipose tissues, mitochondrial dysfunction is the primary cause of …