Research progress on the mechanism of orexin in pain regulation in different brain regions
X Kang, H Tang, Y Liu, Y Yuan, M Wang - Open Life Sciences, 2021 - degruyter.com
Orexin is a neuropeptide that is primarily synthesized and secreted by the lateral
hypothalamus (LH) and includes two substances derived from the same precursor (orexin A …
hypothalamus (LH) and includes two substances derived from the same precursor (orexin A …
Hippocampal orexin receptors: Localization and function
ME Salmani, M Sarfi, I Goudarzi - Vitamins and Hormones, 2022 - Elsevier
Orexin (hypocretin) is secreted from the perifornical/lateral hypothalamus and is well known
for sleep regulation. Orexin has two, orexin A and B, transcripts and two receptors, type 1 …
for sleep regulation. Orexin has two, orexin A and B, transcripts and two receptors, type 1 …
Ketamine relieves depression-like behaviors induced by chronic postsurgical pain in rats through anti-inflammatory, anti-oxidant effects and regulating BDNF …
Y Yang, Y Song, X Zhang, W Zhao, T Ma, Y Liu… - …, 2020 - Springer
Rationale Clinically, chronic postsurgical pain (CPSP) is very common. Many CPSP patients
may experience depression. Thus far, little is known about the mechanism of the comorbidity …
may experience depression. Thus far, little is known about the mechanism of the comorbidity …
Effects of bright light therapy on neuroinflammatory and neuroplasticity markers in a diurnal rodent model of Seasonal Affective Disorder
A Costello, K Linning-Duffy, C Vandenbrook… - Annals of …, 2023 - Taylor & Francis
Background Bright light therapy (BLT) is widely used for treating Seasonal Affective Disorder
(SAD). However, the neural mechanisms underlying the therapeutic effects of BLT remain …
(SAD). However, the neural mechanisms underlying the therapeutic effects of BLT remain …
[HTML][HTML] The ability of orexin-A to modify pain-induced cyclooxygenase-2 and brain-derived neurotrophic factor expression is associated with its ability to inhibit …
F Shahsavari, M Abbasnejad… - The Korean Journal …, 2022 - synapse.koreamed.org
Background The rostral ventromedial medulla (RVM) is a critical region for the management
of nociception. The RVM is also involved in learning and memory processes due to its …
of nociception. The RVM is also involved in learning and memory processes due to its …
Methyl jasmonate ameliorates pain‐induced learning and memory impairments through regulating the expression of genes involved in neuroinflammation
F Mohammadinia, S Esmaeili‐Mahani… - Brain and …, 2024 - Wiley Online Library
Objective Orofacial pain with high prevalence is one of the substantial human health issues.
The importance of this matter became more apparent when it was revealed that orofacial …
The importance of this matter became more apparent when it was revealed that orofacial …
Role of hippocampal orexin receptors in antinociception elicited by chemical stimulation of the lateral hypothalamus in the tail-flick test
A Zargarani, S Karimi-Haghighi… - Behavioural brain research, 2021 - Elsevier
The lateral hypothalamus (LH) orexinergic neurons project to numerous brain regions
implicated in pain perception, including the CA1 part of the hippocampal formation …
implicated in pain perception, including the CA1 part of the hippocampal formation …
Cannabidiol in the dorsal hippocampus attenuates emotional and cognitive impairments related to neuropathic pain: Role of prelimbic neocortex-hippocampal …
Background and purpose Chronic neuropathic pain (NP) is commonly associated with
cognitive and emotional impairments. Cannabidiol (CBD) presents a broad spectrum of …
cognitive and emotional impairments. Cannabidiol (CBD) presents a broad spectrum of …
Mode of delivery alters dental pulp nociception and pain-induced changes in cognitive performance in adults male rats
E Mohamadi-Jorjafki, M Abbasnejad… - Canadian journal of …, 2020 - cdnsciencepub.com
This study examined the effects of delivery mode on the response to inflammatory pulpal
pain and pain-induced changes in cognitive performance in adult rats. Experiments were …
pain and pain-induced changes in cognitive performance in adult rats. Experiments were …
Blockage of ventrolateral periaqueductal gray matter cannabinoid 1 receptor increases dental pulp pain and pain-related subsequent learning and memory deficits in …
Abstract Cannabinoid 1 receptor (CB1R) signaling has a pivotal role in the modulation of
both pain and cognitive responses. This study aims at investigating the role of CB1R in the …
both pain and cognitive responses. This study aims at investigating the role of CB1R in the …