[PDF][PDF] The bacterial guide to designing a diversified gene portfolio

KA Innamorati, JP Earl, SD Aggarwal… - … and evolution of …, 2020 - library.oapen.org
The stunning ability of bacteria to evolve and adapt has contributed to the success of these
single cells, which have inhabited the Earth for billions of years and play vital roles in the …

Beyond the pan-genome: current perspectives on the functional and practical outcomes of the distributed genome hypothesis

JA Hammond, EA Gordon, KM Socarras… - Biochemical Society …, 2020 - portlandpress.com
The principle of monoclonality with regard to bacterial infections was considered immutable
prior to 30 years ago. This view, espoused by Koch for acute infections, has proven …

A novel streptococcal cell–cell communication peptide promotes pneumococcal virulence and biofilm formation

RA Cuevas, R Eutsey, A Kadam… - Molecular …, 2017 - Wiley Online Library
Streptococcus pneumoniae (pneumococcus) is a major human pathogen. It is a common
colonizer of the human respiratory track, where it utilizes cell–cell communication systems to …

Promiscuous signaling by a regulatory system unique to the pandemic PMEN1 pneumococcal lineage

A Kadam, RA Eutsey, J Rosch, X Miao… - PLoS …, 2017 - journals.plos.org
Streptococcus pneumoniae (pneumococcus) is a leading cause of death and disease in
children and elderly. Genetic variability among isolates from this species is high. These …

Pneumococcal attachment to epithelial cells is enhanced by the secreted peptide VP1 via its control of hyaluronic acid processing

RA Cuevas, E Ebrahimi, O Gazioglu, H Yesilkaya… - bioRxiv, 2019 - biorxiv.org
ABSTRACT The Gram-positive bacterium Streptococcus pneumoniae (pneumococcus) is an
important human pathogen. It can either asymptomatically colonize the nasopharynx or …

Investigations into the Role of Inter and Intra Strain Quorum Sensing in Pneumococcal Pathogenesis

A Kadam - 2017 - search.proquest.com
Streptococcus pneumoniae is the leading cause of pediatric morbidity and mortality
worldwide. The rich genomic diversity among strains of pneumococci contributes to varied …