Understanding the healthy and diseased state of skin is important in many areas of basic
and applied research. Although the field of skin tissue engineering has advanced greatly …

Myocardial infarction is one of the major causes of morbidity and mortality worldwide.
Current treatments can relieve the symptoms of myocardial ischemia but cannot repair the …

The aim of this study was the design of a 3D scaffold composed of poly (vinyl) alcohol (PVA)
for cardiac tissue engineering (CTE) applications. The PVA scaffold was fabricated using a …

Induced pluripotent stem cells (iPSCs) originate from the reprogramming of adult somatic
cells using four Yamanaka transcription factors. Since their discovery, the stem cell (SC) field …

The recent progress in derivation of pluripotent stem cells (PSCs) from farm animals opens
new approaches not only for reproduction, genetic engineering, treatment and conservation …

Recent advances in induced pluripotent stem cell technologies and phenotypic screening
shape the future of bioactive small-molecule discovery. In this review we analyze the impact …

Regenerative medicine represents the forefront of health sciences and holds promises for
the treatment and, possibly, the cure of a number of challenging conditions. It relies on the …

An important component for successful translation of cell replacement‐based therapies into
clinical practice is the utilization of large animal models to conduct efficacy and/or safety cell …

An outstanding amount of resources has been used in research on manipulation of human
stem cells, especially mesenchymal stem cells (MSCs), for various clinical applications …

Human pluripotent stem cell (hPSC)-derived neural cultures have attracted interest for
modeling epilepsy and seizure-like activity in vitro. Clinical and experimental evidence have …