Thioredoxin (TRX) is a dithiol-reducing enzyme that is induced by various oxidative stresses.
TRX regulates the activity of DNA-binding proteins, including Jun/Fos and nuclear factor-κB …

We have recently reported that Ginsenoside Rh2 (G-Rh2) induces the activation of two
initiator caspases, caspase-8 and caspase-9 in human cancer cells. However, the molecular …

The relationship between apoptosis, apoptosis regulatory proteins, cell proliferation and
human papillomavirus infection during various phases of tumor progression in the uterine …

Abstract The synthetic retinoid 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphthalene
carboxylic acid (CD437) induces apoptosis in a variety of cancer cells. Recently, we …

The INK4A/ARF locus on chromosome 9 is a tumor suppressor gene frequently mutated in
human cancers. In order to study the effects of p14ARF expression in tumor cells, we …

The present study investigated the effects of curcumin (Cur) on growth of human cervical
cancer xenograft in nude mice and underlying mechanism. The nude mice modeled with …

Fas is expressed in various cells and transduces the cell death signal. p21 is a mediator of
p53-dependent G1 arrest associated with deoxyribonucleic acid (DNA) damage. The …

Objective (s): To analyze aberrant expression of the apoptotic protein p53 and the anti-
apoptotic protein Bcl-2 in premalignant lesions of the uterine cervix induced by human …

The present study investigated the effects of curcumin (Cur) on growth of human cervical
cancer xenograft in nude mice and underlying mechanism. The nude mice modeled with …

The developing cerebral cortical neuroepithelium undergoes overlapping periods of
neurogenesis, suicide and cell migration to establish the mature cortical plate. The present …