Aging is a phenomenon that all living organisms inevitably face. Every year, 9.9 million
people, globally, suffer from dementia, an indicator of the aging brain. Brain aging is …

With the global increase of the elderly population, the improvement of the treatment for
various aging-related diseases and the extension of a healthy lifespan have become some …

Ageing is a strong independent risk factor for disability, morbidity and mortality. Post‐mitotic
cells including those in the heart are a particular risk to age‐related deterioration. As the …

Polygonatum sibiricum polysaccharides (PSP), the extract of Polygonatum sibiricum, are
demonstrated to exhibit a wide range of pharmacological activities. A recent study reported …

Bicarbonate is one of the major anions in mammalian tissues and fluids, is utilized by
various exchangers to transport other ions and organic substrates across cell membranes …

Ageing is a crucial risk factor for the development of age‐related cardiovascular diseases.
Therefore, the molecular mechanisms of ageing and novel anti‐ageing interventions need to …

Spermidine (SPD) is a natural polyamine present in all living organisms and is involved in
the maintenance of cellular homeostasis by inducing autophagy in different model …

The population of obese-elderly has increased prominently around the world. Both aging
and obesity are major factors of neurodegeneration. The present study hypothesizes that …

Longitudinal studies are mandatory to study aging, however, they have certain drawbacks,
for example, they require strict maintenance that is expensive given the breeding time …

We aimed to investigate the effect of chronic D-galactose exposure on the mimicking of
natural aging processes based upon the hallmarks of aging. Seven-week-old male Wistar …