Targeting ferroptosis in acute kidney injury

L Ni, C Yuan, X Wu - Cell Death & Disease, 2022 - nature.com
Acute kidney injury (AKI) is a major public health problem with high incidence and mortality.
As a form of programmed cell death (PCD), ferroptosis could be considered as a process of …

Continuous renal replacement therapy: who, when, why, and how

S Tandukar, PM Palevsky - Chest, 2019 - Elsevier
Continuous renal replacement therapy (CRRT) is commonly used to provide renal support
for critically ill patients with acute kidney injury, particularly patients who are …

World incidence of AKI: a meta-analysis

P Susantitaphong, DN Cruz, J Cerda… - Clinical journal of the …, 2013 - journals.lww.com
Results There were 312 studies identified (n= 49,147,878), primarily in hospital settings.
Most studies originated from North America, Northern Europe, and Eastern Asia, from high …

[PDF][PDF] Acute kidney injury—epidemiology, outcomes and economics

O Rewa, SM Bagshaw - Nature reviews nephrology, 2014 - nature.com
Acute kidney injury (AKI) is a widespread problem of epidemic status. Compelling evidence
indicates that the incidence of AKI is rapidly increasing, particularly among hospitalized …

A Bright, Renal‐Clearable NIR‐II Brush Macromolecular Probe with Long Blood Circulation Time for Kidney Disease Bioimaging

C Yao, Y Chen, M Zhao, S Wang, B Wu… - Angewandte …, 2022 - Wiley Online Library
Early detection of kidney disease is of vital importance due to its current prevalence
worldwide. Fluorescence imaging, especially in the second near‐infrared window (NIR‐II) …

International Society of Nephrology's 0by25 initiative for acute kidney injury (zero preventable deaths by 2025): a human rights case for nephrology

RL Mehta, J Cerdá, EA Burdmann, M Tonelli… - The Lancet, 2015 - thelancet.com
Executive summary Acute kidney injury (AKI) is a major contributor to poor patient outcomes.
AKI occurs in about 13· 3 million people per year, 85% of whom live in the developing world …

Regulated cell death in AKI

A Linkermann, G Chen, G Dong… - Journal of the …, 2014 - journals.lww.com
AKI is pathologically characterized by sublethal and lethal damage of renal tubules. Under
these conditions, renal tubular cell death may occur by regulated necrosis (RN) or …

Immune cells and inflammation in AKI to CKD progression

Y Sato, M Yanagita - American Journal of Physiology-Renal …, 2018 - journals.physiology.org
Acute kidney injury (AKI) is a common clinical state resulting from pathogenic conditions
such as ischemic and toxic insults. The pathophysiology of AKI shares common pathogenic …

The role of acute kidney injury in chronic kidney disease

RK Hsu, CY Hsu - Seminars in nephrology, 2016 - Elsevier
There is increasing recognition that acute kidney injury (AKI) and chronic kidney disease
(CKD) are closely linked and likely promote one another. Underlying CKD now is …

Validation of cell-cycle arrest biomarkers for acute kidney injury using clinical adjudication

A Bihorac, LS Chawla, AD Shaw… - American journal of …, 2014 - atsjournals.org
Rationale: We recently reported two novel biomarkers for acute kidney injury (AKI), tissue
inhibitor of metalloproteinases (TIMP)-2 and insulin-like growth factor binding protein 7 …