Genetic polymorphisms of ACE1, ACE2, and TMPRSS2 associated with COVID‐19 severity: A systematic review with meta‐analysis

W Saengsiwaritt, J Jittikoon… - Reviews in medical …, 2022 - Wiley Online Library
Abstract Novel coronavirus disease 2019 (COVID‐19) poses a global threat, due to its
fluctuating frequency and lethality. Published data revealed associations of COVID‐19 …

Systematic review and meta-analysis of human genetic variants contributing to COVID-19 susceptibility and severity

K Gupta, G Kaur, T Pathak, I Banerjee - Gene, 2022 - Elsevier
The COVID-19 pandemic has spawned global health crisis of unprecedented magnitude,
claiming millions of lives and pushing healthcare systems in many countries to the brink …

TMPRSS2 polymorphism (rs12329760) and the severity of the COVID-19 in Iranian population

A Yaghoobi, JS Lord, JS Rezaiezadeh… - PLoS …, 2023 - journals.plos.org
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has been responsible for
the recent pandemic since early 2020. Due to the wide range of clinical symptoms of this …

Genetic polymorphisms associated with susceptibility to COVID-19 disease and severity: A systematic review and meta-analysis

C Dieter, LA Brondani, CB Leitão, F Gerchman… - PLoS …, 2022 - journals.plos.org
Although advanced age and presence of comorbidities significantly impact the variation
observed in the clinical symptoms of COVID-19, it has been suggested that genetic variants …

Polymorphisms in ACE1, TMPRSS2, IFIH1, IFNAR2, and TYK2 Genes Are Associated with Worse Clinical Outcomes in COVID-19

C Dieter, L de Almeida Brondani, NE Lemos… - Genes, 2022 - mdpi.com
Although advanced age, male sex, and some comorbidities impact the clinical course of
COVID-19, these factors only partially explain the inter-individual variability in disease …

Genetic polymorphisms of ACE1, ACE2, IFTM3, TMPRSS2 and TNFα genes associated with susceptibility and severity of SARS-CoV-2 infection: A systematic review …

V Pecoraro, M Cuccorese, T Trenti - Clinical and Experimental Medicine, 2023 - Springer
Background Some human polymorphisms of ACE1, ACE2, IFITM3, TMPRSS2 and TNFα
genes may have an effect on the susceptibility to SARS-CoV-2 infection and increase the …

Genetic association between ACE2 (rs2285666 and rs2074192) and TMPRSS2 (rs12329760 and rs2070788) polymorphisms with post-COVID symptoms in …

C Fernández-De-Las-Peñas, L Arendt-Nielsen… - Genes, 2022 - mdpi.com
The aim of the study was to identify the association between four selected COVID-19
polymorphisms of ACE2 and TMPRSS2 receptors genes with the presence of long-COVID …

[HTML][HTML] The association of ACE1, ACE2, TMPRSS2, IFITM3 and VDR polymorphisms with COVID-19 severity: A systematic review and meta-analysis

Z Dobrijevic, D Robajac, N Gligorijevic, M Šunderic… - EXCLI …, 2022 - ncbi.nlm.nih.gov
Genes involved in the regulation of viral recognition and its entry into a host cell have been
identified as candidates for genetic association studies on COVID-19 severity. Published …

Host genetic diversity and genetic variations of SARS-CoV-2 in COVID-19 pathogenesis and the effectiveness of vaccination

M Delshad, MJ Sanaei… - International …, 2022 - Elsevier
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), responsible for the
outbreak of coronavirus disease 2019 (COVID-19), has shown a vast range of clinical …

[HTML][HTML] Polymorphism of tmprss2 (rs12329760) but not ace2 (rs4240157), tmprss11a (rs353163) and cd147 (rs8259) is associated with the severity of COVID-19 in …

O Izmailova, O Shlykova, A Kabaliei… - Acta Bio Medica …, 2023 - ncbi.nlm.nih.gov
Methods: The study population consisted of the Ukrainian population with COVID-19:
patients without oxygen therapy (n= 62), with non-invasive (n= 92) and invasive (n= 35) …