Infections caused by multidrug-resistant (MDR) and extensively drug-resistant (XDR) Gram-
negative bacteria (GNB), including carbapenem-resistant (CR) Enterobacterales (CRE; …

The rapid spread of multidrug-resistant Gram-negative organisms constitutes one of the
greatest challenges to global health. While Gram-negative organisms have developed …

Abstract Background The Infectious Diseases Society of America (IDSA) is committed to
providing up-to-date guidance on the treatment of antimicrobial-resistant infections. The …

Background Antimicrobial-resistant infections are commonly encountered in US hospitals
and result in significant morbidity and mortality. This guidance document provides …

Carbapenem-resistant Enterobacteriaceae (CRE) infection is highly endemic in China, but
estimates of the infection burden are lacking. We established the incidence of CRE infection …

Summary Background Carbapenem-resistant Enterobacterales (CRE) are a global threat.
We aimed to describe the clinical and molecular characteristics of Centers for Disease …

Lower respiratory tract infections, including hospital-acquired and ventilator-associated
pneumonia, are common in hospitalized patient populations. Standard methods frequently …

The ability of clinical microbiology laboratories to reliably detect carbapenemase-producing
carbapenem-resistant Enterobacteriaceae (CP-CRE) is an important element of the effort to …

Abstract Multidrug-resistant (MDR) Gram-negative bacteria (GNB) pose a critical threat to
global healthcare, worsening outcomes and increasing mortality among infected patients …

Abstract Objective Ceftazidime–avibactam (CAZ-AVI) is a novel synthetic β-lactamase
inhibitor combination. Although the combination has been available clinically for only a few …