Global threat of carbapenem-resistant gram-negative bacteria
Infections caused by multidrug-resistant (MDR) and extensively drug-resistant (XDR) Gram-
negative bacteria (GNB), including carbapenem-resistant (CR) Enterobacterales (CRE; …
negative bacteria (GNB), including carbapenem-resistant (CR) Enterobacterales (CRE; …
[HTML][HTML] Clinical data from studies involving novel antibiotics to treat multidrug-resistant Gram-negative bacterial infections
Abstract Multidrug-resistant (MDR) Gram-negative bacteria (GNB) pose a critical threat to
global healthcare, worsening outcomes and increasing mortality among infected patients …
global healthcare, worsening outcomes and increasing mortality among infected patients …
Infectious Diseases Society of America 2022 guidance on the treatment of extended-spectrum β-lactamase producing Enterobacterales (ESBL-E), carbapenem …
Abstract Background The Infectious Diseases Society of America (IDSA) is committed to
providing up-to-date guidance on the treatment of antimicrobial-resistant infections. The …
providing up-to-date guidance on the treatment of antimicrobial-resistant infections. The …
Infectious Diseases Society of America guidance on the treatment of extended-spectrum β-lactamase producing Enterobacterales (ESBL-E), carbapenem-resistant …
Background Antimicrobial-resistant infections are commonly encountered in US hospitals
and result in significant morbidity and mortality. This guidance document provides …
and result in significant morbidity and mortality. This guidance document provides …
Epidemiology of carbapenem-resistant Enterobacteriaceae infections: report from the China CRE Network
Carbapenem-resistant Enterobacteriaceae (CRE) infection is highly endemic in China, but
estimates of the infection burden are lacking. We established the incidence of CRE infection …
estimates of the infection burden are lacking. We established the incidence of CRE infection …
Molecular and clinical epidemiology of carbapenem-resistant Enterobacterales in the USA (CRACKLE-2): a prospective cohort study
Summary Background Carbapenem-resistant Enterobacterales (CRE) are a global threat.
We aimed to describe the clinical and molecular characteristics of Centers for Disease …
We aimed to describe the clinical and molecular characteristics of Centers for Disease …
Modified carbapenem inactivation method for phenotypic detection of carbapenemase production among Enterobacteriaceae
The ability of clinical microbiology laboratories to reliably detect carbapenemase-producing
carbapenem-resistant Enterobacteriaceae (CP-CRE) is an important element of the effort to …
carbapenem-resistant Enterobacteriaceae (CP-CRE) is an important element of the effort to …
[HTML][HTML] Resistance to ceftazidime–avibactam and underlying mechanisms
Y Wang, J Wang, R Wang, Y Cai - Journal of global antimicrobial resistance, 2020 - Elsevier
Abstract Objective Ceftazidime–avibactam (CAZ-AVI) is a novel synthetic β-lactamase
inhibitor combination. Although the combination has been available clinically for only a few …
inhibitor combination. Although the combination has been available clinically for only a few …
Phenotypic detection of carbapenemase-producing organisms from clinical isolates
The rapid spread of multidrug-resistant Gram-negative organisms constitutes one of the
greatest challenges to global health. While Gram-negative organisms have developed …
greatest challenges to global health. While Gram-negative organisms have developed …
[PDF][PDF] Infectious Diseases Society of America antimicrobial resistant treatment guidance: gram-negative bacterial infections
The rise in antimicrobial resistance (AMR) continues to be a global crisis [1, 2]. Collectively,
antimicrobial resistant pathogens caused more than 2.8 million infections and over 35,000 …
antimicrobial resistant pathogens caused more than 2.8 million infections and over 35,000 …