A review of genome-based precision medicine efforts within the Department of Defense

L Poon, ED Por, HJ Cho, TG Oliver - Military medicine, 2022 - academic.oup.com
Introduction Providing patient-specific clinical care is an expanding focus for medical
professionals and researchers, more commonly referred to as personalized or precision …

Precision health research and implementation reviewed through the conNECT framework

U Menon, E Cohn, CA Downs, SM Gephart, L Redwine - Nursing Outlook, 2019 - Elsevier
Background Precision health is a population-based approach that incorporates big-data
strategies to understand the complex interactions between biological, environmental …

A multidimensional bioinformatic platform for the study of human response to surgery

AM Eckhoff, AA Connor, JKM Thacker… - Annals of …, 2022 - journals.lww.com
Objective: To design and establish a prospective biospecimen repository that integrates
multi-omics assays with clinical data to study mechanisms of controlled injury and healing …

Immune response profiling in patients with traumatic injuries associated with alcohol ingestion

AW Breslin, AT Limkakeng, E Silvius… - Clinical and …, 2021 - Wiley Online Library
Traumatic injuries afflict more than 5 million people globally every year. Current and past
animal research has demonstrated association among alcohol, trauma, and impaired …

An integrative model using flow cytometry identifies nosocomial infection after trauma

RB Gelbard, H Hensman, S Schobel… - Journal of Trauma …, 2021 - journals.lww.com
BACKGROUND Flow cytometry (FCM) is a rapid diagnostic tool for monitoring immune cell
function. We sought to determine if assessment of cell phenotypes using standardized FCM …

Multidimensional machine learning models predicting outcomes after trauma

D Moris, R Henao, H Hensman, L Stempora, S Chasse… - Surgery, 2022 - Elsevier
Background An emerging body of literature supports the role of individualized prognostic
tools to guide the management of patients after trauma. The aim of this study was to develop …

[HTML][HTML] Association of a Network of Immunologic Response and Clinical Features With the Functional Recovery From Crotalinae Snakebite Envenoming

CJ Gerardo, E Silvius, S Schobel… - Frontiers in …, 2021 - frontiersin.org
Background The immunologic pathways activated during snakebite envenoming (SBE) are
poorly described, and their association with recovery is unclear. The immunologic response …

Precision Medicine in the Intensive Care Unit: Identifying Opportunities and Overcoming Barriers

TL Palmieri, NK Tran - Annual Update in Intensive Care and Emergency …, 2019 - Springer
Is precision medicine really precise? Precision in medicine can only be achieved with
precision diagnostics. Unfortunately, barriers such as access to clean electronic medical …