Objective To review the current literature about the epidemiology, clinical presentation,
diagnosis, and treatment of laryngopharyngeal reflux (LPR). Data Sources PubMed …

There is a perception that the prevalence of gastroesophageal reflux disease (GERD) is
increasing, but few studies have directly tackled this issue. By using a systematic approach …

Objective—This report describes ambulatory care visits made to physician offices in the
United States. Statistics are presented on selected characteristics of the physician's practice …

Introduction Laryngopharyngeal reflux (LPR) is a highly prevalent disease and commonly
encountered in the otolaryngologist's office. Objective To review the literature on the …

Objectives: Laryngopharyngeal reflux (LPR) is an expensive, high-prevalence disease with
a high rate of medical treatment failure. In the past, it was mistakenly believed that pepsin …

Abstract Objectives/Hypothesis: To estimate the annual direct costs associated with the
diagnosis and management of laryngeal disorders. Study Design: Retrospective analysis of …

OBJECTIVE: To determine the efficacy of proton pump inhibitor (PPI) therapy with
esomeprazole on symptoms and signs associated with laryngopharyngeal reflux (LPR) …

Objectives: At the cellular level, tissue-bound pepsin is fundamental to the pathophysiologic
mechanism of reflux disease, and although the thresholds for laryngeal damage in …

Objectives: We undertook to 1) obtain unequivocal evidence to confirm or rebut our initial
observations that pepsin is taken up by hypopharyngeal epithelial cells by receptor …

We aimed to systematically review the randomized controlled trials (RCTs) regarding the
therapeutic efficiency of proton pump inhibitor (PPI) therapy for laryngopharyngeal reflux …