The safe sedation of children for procedures requires a systematic approach that includes
the following: no administration of sedating medication without the safety net of …

In 2010, under the guidance of the DGAI (German Society of Anaesthesiology and Intensive
Care Medicine) and DIVI (German Interdisciplinary Association for Intensive Care and …

Background Preclinical data suggest that general anaesthetics affect brain development.
There is mixed evidence from cohort studies that young children exposed to anaesthesia …

The number of diagnostic and minor surgical procedures performed on pediatric patients
outside of the traditional operating room setting has increased in the past several decades …

Background: Animal studies demonstrate general anesthetic (GA) toxicity in the developing
brain. Clinical reports raise concern, but the risk of GA exposure to neurodevelopment in …

Cerebral oxygenation is not always reflected by systemic arterial oxygenation. Therefore,
regional cerebral oxygen saturation (rScO2) monitoring with near-infrared spectroscopy …

OBJECTIVE: This study aimed to determine the incidence and potential risk factors for
developmental delay after neonatal surgery for major NCCA. DATA SOURCES: A systematic …

Effective and safe drug administration in neonates should be based on integrated
knowledge on the evolving physiological characteristics of the infant who will receive the …

Ketamine, an N-methyl-D-aspartate (NMDA) receptor antagonist, is widely used in pediatric
anesthesia. Recently, a series of animal studies have shown that ketamine may have …

When does the mind begin? Infant psychology is mysterious in part because we cannot
remember our first months of life, nor can we directly communicate with infants. Even more …