Inositols' importance in the improvement of the endocrine–metabolic profile in PCOS

A Wojciechowska, A Osowski, M Jóźwik… - International journal of …, 2019 - mdpi.com
Polycystic ovary syndrome (PCOS) is one of the most common causes of infertility and
metabolic problems among women of reproductive age. The mechanism of PCOS is …

CYP17 T/C (rs74357) gene polymorphism contributes to polycystic ovary syndrome susceptibility: evidence from a meta-analysis

X Liu, M Xu, M Qian, L Yang - Endocrine Connections, 2021 - ec.bioscientifica.com
The cytochrome P450 family 17 (CYP17) is associated with hyperandrogenism in women,
and the association between CYP17 gene polymorphism and the risk of polycystic ovary …

lncRNA FDNCR promotes apoptosis of granulosa cells by targeting the miR-543-3p/DCN/TGF-β signaling pathway in Hu sheep

X Yao, XX Gao, Y Bao, MA El-Samahy, J Yang… - … Therapy-Nucleic Acids, 2021 - cell.com
Long non-coding RNAs (lncRNAs) regulate the development of follicles and reproductive
diseases, but the mechanisms by which lncRNAs regulate ovarian functions and fertility …

[PDF][PDF] Linum usitatissimum seeds oil down-regulates mRNA expression for the steroidogenic acute regulatory protein and Cyp11A1 genes, ameliorating letrezole …

SR Emam, RM Abd-Elsalam, AA Azouz… - J Physiol …, 2021 - scholar.cu.edu.eg
The safety and effectiveness of nutricetics suggest that they may offer an alternative to
pharmaceutical and surgical therapy for hormone-dependent disorders, such as polycystic …

[PDF][PDF] Effects of thyroid dysfunction on reproductive hormones in female rats

J Liu, M Guo, X Hu, X Weng, Y Tian, K Xu, D Heng… - Chin J Physiol, 2018 - cps.org.tw
Thyroid hormones (THs) play a critical role in the development of ovarian cells. Although the
effects of THs on female reproduction are of great interest, the mechanism remains unclear …

Hypomethylation of specific CpG sites in the promoter region of steroidogeneic genes (GATA6 and StAR) in prenatally androgenized rats

MS Jahromi, JW Hill, FR Tehrani, A Zadeh-Vakili - Life sciences, 2018 - Elsevier
Introduction The methylation level of promoters is one of the most studied and well-known
epigenetic mechanisms that programs the amount of gene expression. Over expression of …

How to choose the suitable animal model of polycystic ovary syndrome?

A Tamadon, W Hu, P Cui, T Ma, X Tong… - … Medicine and Modern …, 2018 - World Scientific
Polycystic ovary syndrome (PCOS) is a gynecological metabolic and endocrine disorder
with uncertain etiology. To understand the etiology of PCOS or the evaluation of various …

Comparative transcriptome analysis provides insight into spatio-temporal expression characteristics and genetic regulatory network in postnatal developing …

Y Zhang, H Wang, W Tu, SH Abbas Raza, J Cao… - Frontiers in …, 2022 - frontiersin.org
The depot differences between Subcutaneous Fat (SAF) and Visceral Fat (VAF) are critical
for human well-being and disease processes in regard to energy metabolism and endocrine …

CYP17A1 rs743572 polymorphism might contribute to endometriosis susceptibility: evidences from a case–control study

L Cong, Q Fu, T Gao - Medicine, 2018 - journals.lww.com
CYP17A1 rs743572 polymorphism might contribute to endometrio... : Medicine CYP17A1
rs743572 polymorphism might contribute to endometriosis susceptibility: evidences from a …

Alteration in follistatin gene expression detected in prenatally androgenized rats

M Salehi Jahromi, F Ramezani Tehrani… - Gynecological …, 2017 - Taylor & Francis
Impaired ovarian follicle development, the hallmark of polycystic ovarian syndrome (PCOS),
is believed to be due to the changes in expression of related genes such as follistatin (FST) …