The cellular and molecular bases of leptin and ghrelin resistance in obesity
Obesity, a major risk factor for the development of diabetes mellitus, cardiovascular diseases
and certain types of cancer, arises from a chronic positive energy balance that is often due to …
and certain types of cancer, arises from a chronic positive energy balance that is often due to …
[HTML][HTML] Adipokines in non-alcoholic fatty liver disease: are we on the road toward new biomarkers and therapeutic targets?
V Francisco, MJ Sanz, JT Real, P Marques… - Biology, 2022 - mdpi.com
Simple Summary Non-alcoholic fatty liver disease (NAFLD) is an unmet medical need due to
its increasingly high incidence, severe clinical consequences, and the absence of feasible …
its increasingly high incidence, severe clinical consequences, and the absence of feasible …
Excess body fat in obese and normal-weight subjects
Excess body adiposity, especially abdominal obesity and ectopic fat accumulation, are key
risk factors in the development of a number of chronic diseases. The advent of in vivo …
risk factors in the development of a number of chronic diseases. The advent of in vivo …
The integrative role of leptin, oestrogen and the insulin family in obesity‐associated breast cancer: potential effects of exercise
S Schmidt, JM Monk, LE Robinson… - Obesity …, 2015 - Wiley Online Library
Obesity is an established risk factor for postmenopausal breast cancer. The mechanisms
through which obesity influences the development and progression of breast cancer are not …
through which obesity influences the development and progression of breast cancer are not …
Relationship of ghrelin and leptin hormones with body mass index and waist circumference in a random sample of adults
V Monti, JJ Carlson, SC Hunt, TD Adams - Journal of the American Dietetic …, 2006 - Elsevier
OBJECTIVE: To evaluate the relationship of ghrelin and leptin hormones with body mass
index (BMI) and waist circumference in a population-based random sample of adult men …
index (BMI) and waist circumference in a population-based random sample of adult men …
[HTML][HTML] Leptin and incident type 2 diabetes: risk or protection?
Aims/hypothesis The aim of this study was to investigate the association of leptin levels with
incident diabetes in middle-aged adults, taking into account factors purportedly related to …
incident diabetes in middle-aged adults, taking into account factors purportedly related to …
Menarche is related to fat distribution
WD Lassek, SJC Gaulin - American journal of physical …, 2007 - Wiley Online Library
The energy demands of pregnancy and lactation together with the accumulation of stored fat
in human females during development suggest that a critical level of fat may be required for …
in human females during development suggest that a critical level of fat may be required for …
Molecular aspects of adipokine-bone interactions
Adipose tissue is an endocrine organ able to produce a wide series of pleiotropic molecules,
defined “adipokines”. In addition to the regulation of food intake and energy metabolism …
defined “adipokines”. In addition to the regulation of food intake and energy metabolism …
Gender differences in sympathetic nervous activity: influence of body mass and blood pressure
Background Obesity and high blood pressure (BP) commonly coexist in patients, and both
conditions are associated with elevated sympathetic nervous activity. We tested whether the …
conditions are associated with elevated sympathetic nervous activity. We tested whether the …
[HTML][HTML] Hydroethanolic Extract of Prunus domestica L.: Metabolite Profiling and In Vitro Modulation of Molecular Mechanisms Associated to Cardiometabolic …
High consumption of fruit and vegetables has an inverse association with cardiometabolic
risk factors. This study aimed to chemically characterize the hydroethanolic extract of P …
risk factors. This study aimed to chemically characterize the hydroethanolic extract of P …