The cellular and molecular bases of leptin and ghrelin resistance in obesity

H Cui, M López, K Rahmouni - Nature Reviews Endocrinology, 2017 - nature.com
Obesity, a major risk factor for the development of diabetes mellitus, cardiovascular diseases
and certain types of cancer, arises from a chronic positive energy balance that is often due to …

[HTML][HTML] Adipokines in non-alcoholic fatty liver disease: are we on the road toward new biomarkers and therapeutic targets?

V Francisco, MJ Sanz, JT Real, P Marques… - Biology, 2022 - mdpi.com
Simple Summary Non-alcoholic fatty liver disease (NAFLD) is an unmet medical need due to
its increasingly high incidence, severe clinical consequences, and the absence of feasible …

Excess body fat in obese and normal-weight subjects

EL Thomas, G Frost, SD Taylor-Robinson… - Nutrition research …, 2012 - cambridge.org
Excess body adiposity, especially abdominal obesity and ectopic fat accumulation, are key
risk factors in the development of a number of chronic diseases. The advent of in vivo …

The integrative role of leptin, oestrogen and the insulin family in obesity‐associated breast cancer: potential effects of exercise

S Schmidt, JM Monk, LE Robinson… - Obesity …, 2015 - Wiley Online Library
Obesity is an established risk factor for postmenopausal breast cancer. The mechanisms
through which obesity influences the development and progression of breast cancer are not …

Relationship of ghrelin and leptin hormones with body mass index and waist circumference in a random sample of adults

V Monti, JJ Carlson, SC Hunt, TD Adams - Journal of the American Dietetic …, 2006 - Elsevier
OBJECTIVE: To evaluate the relationship of ghrelin and leptin hormones with body mass
index (BMI) and waist circumference in a population-based random sample of adult men …

[HTML][HTML] Leptin and incident type 2 diabetes: risk or protection?

MI Schmidt, BB Duncan, A Vigo, JS Pankow, D Couper… - Diabetologia, 2006 - Springer
Aims/hypothesis The aim of this study was to investigate the association of leptin levels with
incident diabetes in middle-aged adults, taking into account factors purportedly related to …

Menarche is related to fat distribution

WD Lassek, SJC Gaulin - American journal of physical …, 2007 - Wiley Online Library
The energy demands of pregnancy and lactation together with the accumulation of stored fat
in human females during development suggest that a critical level of fat may be required for …

Molecular aspects of adipokine-bone interactions

P Magni, E Dozio, E Galliera… - Current molecular …, 2010 - ingentaconnect.com
Adipose tissue is an endocrine organ able to produce a wide series of pleiotropic molecules,
defined “adipokines”. In addition to the regulation of food intake and energy metabolism …

Gender differences in sympathetic nervous activity: influence of body mass and blood pressure

E Lambert, N Straznicky, N Eikelis, M Esler… - Journal of …, 2007 - journals.lww.com
Background Obesity and high blood pressure (BP) commonly coexist in patients, and both
conditions are associated with elevated sympathetic nervous activity. We tested whether the …

[HTML][HTML] Hydroethanolic Extract of Prunus domestica L.: Metabolite Profiling and In Vitro Modulation of Molecular Mechanisms Associated to Cardiometabolic …

H Ullah, E Sommella, C Santarcangelo, D D'Avino… - Nutrients, 2022 - mdpi.com
High consumption of fruit and vegetables has an inverse association with cardiometabolic
risk factors. This study aimed to chemically characterize the hydroethanolic extract of P …