Metastasis is the major cause of death in patients with colorectal carcinoma (CRC). The
most common sites of metastasis are the liver and the peritoneum. Peritoneal …

Background There is no consensus regarding the appropriate management of asymptomatic
and minimally symptomatic patients with stage IV colorectal cancer and irresectable …

Anoikis is a critical obstacle to cancer metastasis. Colorectal cancer (CRC) exhibits a high
rate of metastasis, leading to death, and the mechanisms involved in anoikis resistance are …

Background Clinical studies regarding colorectal cancer (CRC) have suggested differences
in metastatic patterns between mucinous adenocarcinoma (MC), signet-ring cell carcinoma …

Background Curcumin is the main active ingredient of the spice turmeric, investigated
extensively for putative anticancer properties. Objectives This phase IIa open-labelled …

More and more evidences suggest that primary colon and rectum tumors should not be
considered as a single disease entity. In this manuscript, we evaluate the metastatic patterns …

Purpose The purpose of this study was to describe the frequency of interventions necessary
to palliate the intact primary tumor in patients who present with synchronous, stage IV …

Aim The incidence, patterns of care and survival were determined in patients with stage IV
colorectal cancer (CRC) in a population‐based series. Method Computer records for …

METHODS This parameter is based on the previous parameter published in 2004. An
organized search of MEDLINE, PubMed, Embase, and the Cochrane Database of Collected …

Background In patients with metastatic colorectal cancer (mCRC) with an asymptomatic
primary tumor, there is no consensus on the indication for resection of the primary tumor …