Solid lipid nanoparticles and nanostructured lipid carriers: A review emphasizing on particle structure and drug release

A Gordillo-Galeano, CE Mora-Huertas - European Journal of Pharmaceutics …, 2018 - Elsevier
Colloidal systems based on lipids have attracted attention during the last two decades as a
delivery method of drugs that are poorly soluble in water. The investigations carried out have …

Nanotechnology-based drug delivery systems for the treatment of Alzheimer's disease

B Fonseca-Santos, MPD Gremião… - International Journal of …, 2015 - Taylor & Francis
Alzheimer's disease is a neurological disorder that results in cognitive and behavioral
impairment. Conventional treatment strategies, such as acetylcholinesterase inhibitor drugs …

Nanoparticles for antiparasitic drug delivery

Y Sun, D Chen, Y Pan, W Qu, H Hao, X Wang, Z Liu… - Drug Delivery, 2019 - Taylor & Francis
As an emerging novel drug carrier, nanoparticles provide a promising way for effective
treatment of parasitic diseases by overcoming the shortcomings of low bioavailability, poor …

Glioblastoma multiforme targeted delivery of docetaxel using bevacizumab-modified nanostructured lipid carriers impair in vitro cell growth and in vivo tumor …

LD Di Filippo, JL Duarte, JH Azambuja… - International journal of …, 2022 - Elsevier
Glioblastoma multiforme (GBM) is the most common malignant brain cancer, characterized
by high invasiveness and poor prognosis. Docetaxel (DTX) is a chemotherapeutic drug with …

Physicochemical characterization of solid lipid nanoparticles (SLNs) prepared by a novel microemulsion technique

RM Shah, F Malherbe, D Eldridge, EA Palombo… - Journal of colloid and …, 2014 - Elsevier
Abstract Hypothesis Solid lipid nanoparticles (SLNs) produced by conventional
microemulsion techniques using thermal heat have specific limitations (eg high …

Potential application of nanotechnology in the treatment, diagnosis, and prevention of schistosomiasis

A Qadeer, H Ullah, M Sohail, SZ Safi… - … in Bioengineering and …, 2022 - frontiersin.org
Schistosomiasis is one of the neglected tropical diseases that affect millions of people
worldwide. Globally, it affects economically poor countries, typically due to a lack of proper …

Key production parameters for the development of solid lipid nanoparticles by high shear homogenization

EB Souto, S Doktorovova, A Zielinska… - Pharmaceutical …, 2019 - Taylor & Francis
In this work, we report the development and optimization of solid lipid nanoparticles (SLN)
production by a simple, fast, and cost-effective high shear homogenization process. A …

Development of solid lipid nanoparticle-loaded polymeric hydrogels containing antioxidant and photoprotective bioactive compounds of safflower (Carthamus …

N Aanisah, S Sulistiawati, YY Djabir, RM Asri… - Langmuir, 2023 - ACS Publications
Safflower (Carthamus tinctorius L.) is a potent natural antioxidant because of active
compounds such as quercetin (QU) and luteolin (LU). These components prevent damage …

Biopharmaceutical characterization of praziquantel cocrystals and cyclodextrin complexes prepared by grinding

M Cugovčan, J Jablan, J Lovrić, D Cinčić… - … of pharmaceutical and …, 2017 - Elsevier
Mechanochemical activation using several different co-grinding additives was applied as a
green chemistry approach to improve physiochemical and biopharmaceutical properties of …

Systematic implementation of quality-by-design (QbD) to develop NSAID-loaded nanostructured lipid carriers for ocular application: preformulation screening studies …

VR Rathod, DA Shah, RH Dave - Drug development and industrial …, 2020 - Taylor & Francis
The objective of the present project was to develop and optimize the Ibuprofen (IBU)-loaded
nanostructured lipid carrier (IBU-NLCs) for sustained-release ocular drug delivery using a …