[PDF][PDF] Evolutionary perspective on mammalian inorganic polyphosphate (polyP) biology
Inorganic polyphosphate (polyP), the polymeric form of phosphate, is attracting ever-growing
attention due to the many functions it appears to perform within mammalian cells. This essay …
attention due to the many functions it appears to perform within mammalian cells. This essay …
Inorganic polyphosphate and the regulation of mitochondrial physiology
RT Da Costa, LM Riggs… - Biochemical Society …, 2023 - portlandpress.com
Inorganic polyphosphate (polyP) is an ancient polymer that is well-conserved throughout
evolution. It is formed by multiple subunits of orthophosphates linked together by …
evolution. It is formed by multiple subunits of orthophosphates linked together by …
[HTML][HTML] Role of mitochondria in the myopathy of juvenile dermatomyositis and implications for skeletal muscle calcinosis
Objectives To elucidate mechanisms contributing to skeletal muscle calcinosis in patients
with juvenile dermatomyositis. Methods A well-characterized cohorts of JDM (n= 68) …
with juvenile dermatomyositis. Methods A well-characterized cohorts of JDM (n= 68) …
COVID‐19 and neurodegeneration: The mitochondrial connection
CA Denaro, YI Haloush, SY Hsiao, JJ Orgera… - Aging …, 2022 - Wiley Online Library
There is still a significant lack of knowledge regarding many aspects of the etiopathology
and consequences of the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) …
and consequences of the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) …
[HTML][HTML] Enzymatic depletion of mitochondrial inorganic polyphosphate (polyP) increases the generation of reactive oxygen species (ROS) and the activity of the …
Inorganic polyphosphate (polyP) is an ancient biopolymer that is well preserved throughout
evolution and present in all studied organisms. In mammals, it shows a high co-localization …
evolution and present in all studied organisms. In mammals, it shows a high co-localization …
[HTML][HTML] Human prune regulates the metabolism of mammalian inorganic polyphosphate and bioenergetics
Inorganic polyphosphate (polyP) is an evolutionarily conserved and ubiquitous polymer that
is present in all studied organisms. PolyP consists of orthophosphates (Pi) linked together by …
is present in all studied organisms. PolyP consists of orthophosphates (Pi) linked together by …
[HTML][HTML] Cannabidiol repairs behavioral and brain disturbances in a model of fetal alcohol spectrum disorder
A Gasparyan, D Navarro, F Navarrete… - Pharmacological …, 2023 - Elsevier
Fetal alcohol spectrum disorder (FASD) includes neuropsychiatric disturbances related to
gestational and lactational ethanol exposure. Available treatments are minimal and do not …
gestational and lactational ethanol exposure. Available treatments are minimal and do not …
No life on this planet without PHB
D Seebach - Helvetica Chimica Acta, 2023 - Wiley Online Library
The history of discovery by Rosetta Reusch of oligo‐and poly‐β‐hydroxybutyrates (OHBs
and PHBs) consisting of less than ca. 150 HB units is described. These 'short …
and PHBs) consisting of less than ca. 150 HB units is described. These 'short …
[HTML][HTML] Modulation of ATP production influences inorganic polyphosphate levels in non-athletes' platelets at the resting state
T Ushiki, T Mochizuki, K Suzuki, M Kamimura… - International Journal of …, 2022 - mdpi.com
Platelets produce inorganic polyphosphate (polyP) upon activation to stimulate blood
coagulation. Some researchers have linked polyP metabolism to ATP production, although …
coagulation. Some researchers have linked polyP metabolism to ATP production, although …
[HTML][HTML] The Glacier Ice Worm, Mesenchytraeus solifugus, Elevates Mitochondrial Inorganic Polyphosphate (PolyP) Levels in Response to Stress
T Osorio, ER Scoma, DH Shain, DS Melissaratos… - Biology, 2022 - mdpi.com
Simple Summary Energy maintenance in living organisms is crucial for survival. The ice-
obligate worm, Mesenchytraeus solifugus, displays an unusual bioenergetic pattern, namely …
obligate worm, Mesenchytraeus solifugus, displays an unusual bioenergetic pattern, namely …