miRNAs orchestration of adrenocortical carcinoma-Particular emphasis on diagnosis, progression and drug resistance

WA El-Dakroury, HM Midan, AI Abulsoud… - … -Research and Practice, 2023 - Elsevier
Adrenocortical carcinoma (ACC) is an uncommon aggressive endocrine malignancy that is
nonetheless associated with significant mortality and morbidity rates because of endocrine …

Adrenocortical carcinoma

T Else, AC Kim, A Sabolch, VM Raymond… - Endocrine …, 2014 - academic.oup.com
Adrenocortical carcinoma (ACC) is a rare endocrine malignancy, often with an unfavorable
prognosis. Here we summarize the knowledge about diagnosis, epidemiology …

MicroRNA therapeutics in cancer: current advances and challenges

S Reda El Sayed, J Cristante, L Guyon, J Denis… - Cancers, 2021 - mdpi.com
Simple Summary Cancer is a complex disease associated with deregulation of numerous
genes. In addition, redundant cellular pathways limit efficiency of monotarget drugs in …

Integrated genomic characterization of adrenocortical carcinoma

G Assié, E Letouzé, M Fassnacht, A Jouinot… - Nature …, 2014 - nature.com
Adrenocortical carcinomas (ACCs) are aggressive cancers originating in the cortex of the
adrenal gland. Despite overall poor prognosis, ACC outcome is heterogeneous,. We …

Analysis of MiR-195 and MiR-497 expression, regulation and role in breast cancer

D Li, Y Zhao, C Liu, X Chen, Y Qi, Y Jiang, C Zou… - Clinical cancer …, 2011 - AACR
Purpose: To investigate expression, regulation, potential role and targets of miR-195 and
miR-497 in breast cancer. Experimental Design: The expression patterns of miR-195 and …

From diagnosis to resistance: a symphony of miRNAs in pheochromocytoma progression and treatment response

EGE Elsakka, A Elshafei, MA Elkady, AM Yehia… - Naunyn-Schmiedeberg's …, 2024 - Springer
Pheochromocytoma (PCC) is a neuroendocrine tumor that produces and secretes
catecholamine from either the adrenal medulla or extra-adrenal locations. MicroRNAs …

microRNA-195 promotes apoptosis and suppresses tumorigenicity of human colorectal cancer cells

L Liu, L Chen, Y Xu, R Li, X Du - Biochemical and biophysical research …, 2010 - Elsevier
Deregulated microRNAs and their roles in cancer development have attracted much
attention. In the present study, we analyzed the roles of miR-195 in colorectal cancer …

Characterization of microRNA expression profiles in normal and osteoarthritic human chondrocytes

S Díaz-Prado, C Cicione, E Muiños-López… - BMC musculoskeletal …, 2012 - Springer
Background Osteoarthritis (OA) is a multifactorial disease characterized by destruction of the
articular cartilage due to environmental, mechanical and genetic components. The genetics …

Integrated analysis identifies microRNA-195 as a suppressor of Hippo-YAP pathway in colorectal cancer

M Sun, H Song, S Wang, C Zhang, L Zheng… - Journal of hematology & …, 2017 - Springer
Background With persistent inconsistencies in colorectal cancer (CRC) miRNAs expression
data, it is crucial to shift toward inclusion of a “pre-laboratory” integrated analysis to expedite …

Serum microRNA signatures identified by Solexa sequencing predict sepsis patients' mortality: a prospective observational study

H Wang, P Zhang, W Chen, D Feng, Y Jia, L Xie - PloS one, 2012 - journals.plos.org
Background Sepsis is the leading cause of death in Intensive Care Units. Novel sepsis
biomarkers and targets for treatment are needed to improve mortality from sepsis …