Microbiome is the community of microorganism that co-live with a host. The human being is
the result of the integration of its genome and the coexistence with millions of …

Methyl-CpG-binding protein 2 (MeCP2) is a transcriptional regulator that is highly abundant
in the brain. It binds to methylated genomic DNA to regulate a range of physiological …

Rett syndrome (RTT) is a rare disease but still one of the most abundant causes for
intellectual disability in females. Typical symptoms are onset at month 6–18 after normal pre …

Although synaptic plasticity in neural circuits is orchestrated by an ocean of genes,
molecules, and proteins, the underlying mechanisms remain poorly understood. Recently, it …

Autism spectrum disorder (ASD) comprises a group of multifactorial neurodevelopmental
disorders primarily characterized by deficits in social interaction and repetitive behavior …

Abstract MECP2 duplication syndrome (MDS), a rare X‐linked genomic disorder affecting
predominantly males, is caused by duplication of the chromosomal region containing the …

Rett syndrome (RTT) is an autism spectrum disorder (ASD) caused by mutations in the X-
linked MECP2 gene that encodes methyl-CpG binding protein 2 (MeCP2). Symptoms range …

Olfactory impairment is a common clinical motif across neurodevelopmental disorders,
suggesting olfactory circuits are particularly vulnerable to disease processes and can …

Epilepsy, one of the most common neurological disorders, often is not well controlled by
current pharmacological and surgical treatments. Sensory neuromodulation, including multi …

The methyl CpG‐binding protein‐2 (MECP2) gene is located on the Xq28 region. Loss of
function mutations or increased copies of MECP2 result in Rett syndrome (RTT) and MECP2 …