Amphetamine toxicities: classical and emerging mechanisms
BK Yamamoto, A Moszczynska… - Annals of the New York …, 2010 - Wiley Online Library
The drugs of abuse, methamphetamine and MDMA, produce long‐term decreases in
markers of biogenic amine neurotransmission. These decreases have been traditionally …
markers of biogenic amine neurotransmission. These decreases have been traditionally …
[HTML][HTML] Oxytocin and social motivation
Humans are fundamentally social creatures who are 'motivated'to be with others. In this
review we examine the role of oxytocin (OT) as it relates to social motivation. OT is …
review we examine the role of oxytocin (OT) as it relates to social motivation. OT is …
[HTML][HTML] HIV tat and neurotoxicity
JE King, EA Eugenin, CM Buckner, JW Berman - Microbes and infection, 2006 - Elsevier
HIV tat is the transactivator of HIV-1, supporting efficient viral replication by stabilizing the
transcription of viral genes. Tat can be released from HIV-infected cells and alter several …
transcription of viral genes. Tat can be released from HIV-infected cells and alter several …
CXCL10‐induced cell death in neurons: role of calcium dysregulation
Chemokines play a key role in the regulation of central nervous system disease. CXCL10
over‐expression has been observed in several neurodegenerative diseases, including …
over‐expression has been observed in several neurodegenerative diseases, including …
Intracellular human immunodeficiency virus Tat expression in astrocytes promotes astrocyte survival but induces potent neurotoxicity at distant sites via axonal …
A Chauhan, J Turchan, C Pocernich… - Journal of Biological …, 2003 - ASBMB
The human immunodeficiency virus (HIV)-Tat protein has been implicated in the
neuropathogenesis of HIV infection. However, its role in modulating astroglial-neuronal …
neuropathogenesis of HIV infection. However, its role in modulating astroglial-neuronal …
Morphine causes rapid increases in glial activation and neuronal injury in the striatum of inducible HIV‐1 Tat transgenic mice
AJ Bruce‐Keller, J Turchan‐Cholewo, EJ Smart… - Glia, 2008 - Wiley Online Library
HIV encephalitis (HIVE) is accompanied by brain inflammation, leukocyte infiltration, and
glial activation, and HIV patients who abuse opiates are more likely to develop HIVE. To …
glial activation, and HIV patients who abuse opiates are more likely to develop HIVE. To …
HIV-associated neurotoxicity and cognitive decline: Therapeutic implications
DR Wallace - Pharmacology & Therapeutics, 2022 - Elsevier
As our understanding of changes to the neurological system has improved, it has become
clear that patients who have contracted human immunodeficiency virus type 1 (HIV-1) can …
clear that patients who have contracted human immunodeficiency virus type 1 (HIV-1) can …
Neuronal toxicity in HIV CNS disease
J Kovalevich, D Langford - Future virology, 2012 - Taylor & Francis
HIV enters the brain during the early stages of initial infection and can result in a
complicated array of diverse neurological dysfunctions. While neuronal injury and loss are at …
complicated array of diverse neurological dysfunctions. While neuronal injury and loss are at …
Role of Tat protein in HIV neuropathogenesis
W Li, G Li, J Steiner, A Nath - Neurotoxicity research, 2009 - Springer
The Tat protein of the human immunodeficiency virus (HIV) has been implicated in the
pathophysiology of the neurocognitive deficits associated with HIV infection. This is the …
pathophysiology of the neurocognitive deficits associated with HIV infection. This is the …
Severe, demyelinating leukoencephalopathy in AIDS patients on antiretroviral therapy
TD Langford, SL Letendre, TD Marcotte, RJ Ellis… - Aids, 2002 - journals.lww.com
Objectives To describe a severe form of demyelinating HIV-associated
leukoencephalopathy in AIDS patients failing highly active antiretroviral therapy (HAART), its …
leukoencephalopathy in AIDS patients failing highly active antiretroviral therapy (HAART), its …