With an increase in the ageing population worldwide, the prevalence of osteoporosis
increases at an alarming rate in both male and female irrespective of their ethnicity. At …

Postmenopausal osteoporosis, mainly caused by osteoclast-induced bone resorption, has
become a global public health burden. Natural compounds are emerging as potential …

Structure model index (SMI) is widely used to measure rods and plates in trabecular bone. It
exploits the change in surface curvature that occurs as a structure varies from spherical …

Osteoporosis is a chronic disease whose symptoms include a reduction in bone strength,
osteopenia, and damage to the bone microstructure. Ferulic acids are natural polyphenols …

Osteoporosis is a major cause of morbidity, mortality, and economic burden worldwide.
Despite being an effective in combating the bone-deteriorating disorders, bisphosphonates …

We investigated the potential of using novel zoledronic acid (ZOL)-hydroxyapatite (HA)
nanoparticle based drug formulation in a rat model of postmenopausal osteoporosis. By a …

Background Propranolol (PPN) is a therapeutic option for the treatment of infantile
hemangiomas. This study aimed at the development of nanoemulsion (NE) containing 1 …

The aim of the present study was to determine the protective effects of resveratrol on a rat
model of osteoporosis and examine the associated mechanisms of its action. Rats were …

Targeting of superior osteogenic drugs to bone is an ideal approach for treatment of
osteoporosis. Here, we investigated the potential of using risedronate/zinc-hydroxyapatite …

Delivery of bisphosphonates-like risedronate has been a major challenge till date due to its
poor bioavailability and gastrointestinal tract adverse effects. In this study, we explored the …