Validity of clinical severity scores for respiratory syncytial virus: a systematic review
Background Respiratory syncytial virus (RSV) is a widespread respiratory pathogen, and
RSV-related acute lower respiratory tract infections are the most common cause of …
RSV-related acute lower respiratory tract infections are the most common cause of …
Infection biomarkers based on metabolomics
R Araújo, LFN Bento, TAH Fonseca, CP Von Rekowski… - Metabolites, 2022 - mdpi.com
Current infection biomarkers are highly limited since they have low capability to predict
infection in the presence of confounding processes such as in non-infectious inflammatory …
infection in the presence of confounding processes such as in non-infectious inflammatory …
The spectrum of clinical biomarkers in severe malaria and new avenues for exploration
LPK Foko, G Narang, S Tamang, J Hawadak, J Jakhan… - Virulence, 2022 - Taylor & Francis
Globally, malaria is a public health concern, with severe malaria (SM) contributing a major
share of the disease burden in malaria endemic countries. In this context, identification and …
share of the disease burden in malaria endemic countries. In this context, identification and …
Genome-wide association study of susceptibility to respiratory syncytial virus hospitalization in young children< 5 years of age
AM Egeskov-Cavling, M Van Wijhe… - The Journal of …, 2024 - academic.oup.com
Background Worldwide, respiratory syncytial virus (RSV) infections are among the most
common causes of infant hospitalization. Host genetic factors influencing the risk and …
common causes of infant hospitalization. Host genetic factors influencing the risk and …
Innate immune activation and circulating inflammatory markers in preschool children
Early childhood is characterised by repeated infectious exposures that result in inflammatory
responses by the innate immune system. In addition, this inflammatory response to infection …
responses by the innate immune system. In addition, this inflammatory response to infection …
Immunomodulatory markers and therapies for the management of infant respiratory syncytial virus infection
RA Loaiza, MA Farías, CA Andrade… - Expert Review of Anti …, 2024 - Taylor & Francis
Introduction The human respiratory syncytial virus (hRSV) is one of childhood diseases'
most common respiratory pathogens and is highly associated with lower respiratory tract …
most common respiratory pathogens and is highly associated with lower respiratory tract …
Host inflammatory response is the major marker of severe respiratory syncytial virus infection in older adults
Objectives We aim to study the viral kinetics and host inflammatory response of RSV
infection in older adults, and their correlation with disease severity. Methods We performed a …
infection in older adults, and their correlation with disease severity. Methods We performed a …
[HTML][HTML] What have we learned from animal studies of immune responses to respiratory syncytial virus infection?
SB Drysdale, RS Thwaites, J Price, D Thakur… - Journal of Clinical …, 2024 - Elsevier
Respiratory syncytial virus (RSV) is a common cause of severe respiratory tract infection at
the extremes of age and in vulnerable populations. However, it is difficult to predict the …
the extremes of age and in vulnerable populations. However, it is difficult to predict the …
Molecular profiling of inflammatory mediators in human respiratory syncytial virus and human bocavirus infection
NA Alkubaisi, IM Aziz, AN Alsaleh, AF Alhetheel… - Genes, 2023 - mdpi.com
Infections due to human respiratory syncytial virus (HRSV) and human bocavirus (HBoV)
can mediate the release of several pro-inflammatory cytokines such as IL-6, IL-8, and TNF-α …
can mediate the release of several pro-inflammatory cytokines such as IL-6, IL-8, and TNF-α …
Nasopharyngeal and Peripheral Blood Type II Interferon Signature Evaluation in Infants during Respiratory Syncytial Virus Infection
F Savino, M Dini, A Clemente, C Calvi, A Pau… - Medicina, 2024 - mdpi.com
Background and Objectives: In this study, we applied one-step real time rt-PCR technology
type II INF signature to blood and nasopharyngeal (NPS) swabs of acute early recovery …
type II INF signature to blood and nasopharyngeal (NPS) swabs of acute early recovery …