DNA methylation in solid tumors: functions and methods of detection

A Martisova, J Holcakova, N Izadi, R Sebuyoya… - International Journal of …, 2021 - mdpi.com
DNA methylation, ie, addition of methyl group to 5′-carbon of cytosine residues in CpG
dinucleotides, is an important epigenetic modification regulating gene expression, and thus …

Pathogenesis of human papillomavirus‐associated mucosal disease

IJ Groves, N Coleman - The Journal of pathology, 2015 - Wiley Online Library
Human papillomaviruses (HPVs) are a necessary cause of carcinoma of the cervix and other
mucosal epithelia. Key events in high‐risk HPV (HRHPV)‐associated neoplastic …

Human papillomavirus DNA methylation as a potential biomarker for cervical cancer

MA Clarke, N Wentzensen, L Mirabello, A Ghosh… - … , biomarkers & prevention, 2012 - AACR
Sexually transmitted carcinogenic human papillomavirus (HPV) infections are extraordinarily
prevalent worldwide. However, most incident HPV infections clear within a few years …

[HTML][HTML] Human papillomaviruses in epigenetic regulations

J Durzynska, K Lesniewicz, E Poreba - Mutation Research/Reviews in …, 2017 - Elsevier
Abstract Human Papillomaviruses (HPVs) are double-stranded DNA viruses, that infect
epithelial cells and are etiologically involved in the development of human cancer. Today …

Human papillomavirus and cervical cancer: biomarkers for improved prevention efforts

VV Sahasrabuddhe, P Luhn, N Wentzensen - Future microbiology, 2011 - Taylor & Francis
While organized screening programs in industrialized countries have significantly reduced
cervical cancer incidence, cytology-based screening has several limitations. Equivocal or …

Elevated methylation of HPV16 DNA is associated with the development of high grade cervical intraepithelial neoplasia

L Mirabello, M Schiffman, A Ghosh… - … journal of cancer, 2013 - Wiley Online Library
We explored the association of human papillomavirus type 16 (HPV16) DNA methylation
with age, viral load, viral persistence and risk of incident and prevalent high grade CIN …

Epigenetic alterations in human papillomavirus-associated cancers

D Soto, C Song, ME McLaughlin-Drubin - Viruses, 2017 - mdpi.com
Approximately 15–20% of human cancers are caused by viruses, including human
papillomaviruses (HPVs). Viruses are obligatory intracellular parasites and encode proteins …

[HTML][HTML] Epigenetics of human papillomaviruses

E Johannsen, PF Lambert - Virology, 2013 - Elsevier
Human papilllomaviruses (HPVs) are common human pathogens that infect cutaneous or
mucosal epithelia in which they cause warts, self-contained benign lesions that commonly …

Methylation of human papillomavirus type 16 genome and risk of cervical precancer in a Costa Rican population

L Mirabello, C Sun, A Ghosh… - Journal of the …, 2012 - academic.oup.com
Background Previous studies have suggested an association between human
papillomavirus type 16 (HPV16) genome methylation and cervical intraepithelial neoplasia …

Differential methylation of the HPV 16 upstream regulatory region during epithelial differentiation and neoplastic transformation

S Vinokurova, M von Knebel Doeberitz - PloS one, 2011 - journals.plos.org
High risk human papillomaviruses are squamous epitheliotropic viruses that may cause
cervical and other cancers. HPV replication depends on squamous epithelial differentiation …