Individual-level longitudinal data on biological, behavioural, and social dimensions are
becoming increasingly available. Typically, these data are analysed using mixed effects …

Background: Per-and polyfluoroalkyl substances (PFAS) are a diverse class of industrial
chemicals with widespread environmental occurrence. Exposure to long-chain PFAS is …

Longitudinal studies are essential tools in medical research. In these studies, variables are
not restricted to single measurements but can be seen as variable-trajectories, either single …

Rationale: Recent evidence highlights the importance of optimal lung development during
childhood for health throughout life. Objectives: To explore the plasticity of individual lung …

This series of simulation studies was designed to assess the impact of misspecifications of
the latent variance–covariance matrix (ie,) and residual structure (ie,) on the accuracy of …

Glioblastoma multiforme (GBM) is the most common malignant adult brain tumor. Standard
GBM treatment includes maximal safe surgical resection with combination radiotherapy and …

Background Food allergy is an increasing public health issue and the most common cause
of life-threatening anaphylactic reactions. Conventional allergy tests assess for the presence …

Attention-deficit/hyperactivity disorder (ADHD) is a prevalent developmental disorder,
associated with a range of long-term impairments. Variation in DNA methylation, an …

Importance Bronchiolitis obliterans syndrome has been associated with increased morbidity
and mortality after allogeneic hematopoietic stem cell transplant (HSCT). Previous studies …

Objectives To identify distinct frailty trajectories (clusters of individuals following a similar
progression of frailty over time) in an aging population and to estimate associations between …